K. Droździok, J. Kabiesz, A. Nowak, Cz. Chowaniec, J. Kulikowska
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引用次数: 0
摘要
采用GenePrint STR系统- silver Stain Detection (Promega)对来自波兰上西利西亚地区的529 ~ 1436例无亲和关系、死亡和活着的成年鼠进行检测,检测到CSF1PO、TPOX、TH01、D16S539、D7S820、D13S317、F13A01、FESFPS、VWA、F13B、LPL等11个STR基因座的等位基因频率和法医学参数。此外,还进行了性别鉴定。杂合度(Ht)、多态信息含量(PIC)、辨别力(PD)、匹配概率(PM)、平均排除机会(MEC)和平均排除概率(MEP)的数值采用Dudek计算机程序(FatRec, High Technical School of Częstochowa,波兰)计算。使用Miller的计算机程序(TFPGA,北亚利桑那大学,弗拉格斯塔夫,美国)通过χ2和精确检验确定与HWE的可能差异。上西里西亚人群与波兰其他人群的等位基因频率采用卡莫迪试验进行比较。
The Upper Silesia (Poland) population and forensic usefulness of 11 autosomal STR loci
Allele frequencies, forensic parameters for the 11 STR loci in GenePrint STR Systems—Silver Stain Detection (Promega): CSF1PO, TPOX, TH01, D16S539, D7S820, D13S317, F13A01, FESFPS, VWA, F13B, LPL were determined in a sample of 529–1436 unrelated, dead and alive adults from the Upper Silesia region (Poland). Furthermore, gender identification was carried out. The values of heterozygosity (Ht), polymorphic information content (PIC), power of discrimination (PD), matching probability (PM), mean exclusion chance (MEC) and mean exclusion probability (MEP) were calculated using Dudek's computer programme (FatRec, High Technical School of Częstochowa, Poland). A possible divergence from HWE was determined by χ2 and exact tests using Miller's computer programme (TFPGA, Northern Arizona University, Flagstaff, USA). Comparison of allele frequencies between the Upper Silesia population and other Polish populations was performed with Carmody's test.