PrEP预防HIV-1的疗效、依从性和副作用

Wanyi Fang, Bongani I. Mphoyi, Dineo R. Motake, Jianxin Liu, Wenshuang Li, F. Mei, S. Lai, Jun Wang
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引用次数: 4

摘要

每年,全世界大约有200万新的艾滋病毒感染报告。大约十年前,一家名为吉利德科学公司的公司发现了一种新的艾滋病预防方法,称为暴露前预防(PrEP)。当高危人群保持高依从性时,PrEP的疗效可高达99%。然而,不良反应时有报道,包括在某些情况下低疗效,坚持困难和药物副作用。本文就PrEP自问世以来的进展进行综述,以期为预防艾滋病提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy, Adherence and Side Effects of PrEP for HIV-1 Prevention
Each year, approximately two million new HIV infections are reported worldwide. About one decade ago, a company called Gilead Sciences Inc. discovered a new HIV prevention method named as pre-exposure prophylaxis (PrEP). When high adherence was kept among high-risk population, PrEP efficacy could reach as high as 99%. However, the adverse effects have been reported from time to time, including low efficacy in certain cases, adherence difficulties and medicinal side effects. In this review, we would summarize the progress of PrEP since its introduction in order to provide insights for HIV prevention.
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