胸苷激酶1与循环肿瘤细胞在恶性实体瘤中的应用

Q4 Medicine
Meijuan Ding
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引用次数: 0

摘要

胸苷激酶1 (Thymidine kinase 1, TK1)与早期恶性肿瘤的发生、肿瘤转移、复发有关,TK1在治疗中的变化也能反映肿瘤对治疗的敏感性。循环肿瘤细胞(CTC)从原发肿瘤或转移性肿瘤中转移到血液中。恶性肿瘤中CTC的出现通常与预后差有关,如转移复发、生存时间短等。TK1和CTC的联合也可以作为生存的独立预测因子。现就TK1和CTC在肿瘤发生发展中的作用进行分析和总结。关键词:胸苷激酶;肿瘤细胞,循环;肿瘤;审查
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of thymidine kinase 1 and circulating tumor cell in malignant solid tumor
Thymidine kinase 1 (TK1) is associated with the occurrence of early malignant tumor, tumor metastasis, recurrence, and the changes of TK1 in the treatment can also reflect the sensitivity of tumor to treatment. Circulating tumor cells (CTC) are removed from the primary tumor or metastatic tumor to blood. The appearance of CTC in malignant tumors is usually related to the poor prognosis, such as metastasis and recurrence, short survival time and so on. The combination of TK1 and CTC can also be used as an independent predictor of survival. Now we analyse and summarize the role of TK1 and CTC in tumorigenesis and development . Key words: Thymidine kinase; Neoplastic cells, circulating; Neoplasms; Review
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来源期刊
中国医师杂志
中国医师杂志 Medicine-Medicine (all)
CiteScore
0.10
自引率
0.00%
发文量
20937
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