{"title":"大蒜提取物(Allium sativum Linn)对表皮葡萄球菌生长抑制区域的影响","authors":"Akbar Diosasqia Putra","doi":"10.33319/AGTEK.V20I1.35","DOIUrl":null,"url":null,"abstract":"Background:Infectious diseases are the main cause of high morbidity and mortality rates, especially in developing countries such as Indonesia.Indonesia is abundant with plants that can be used as herbal medicine. Garlic is known as having antibacterial elements, one of them is for Staphylococcus epidermidis which is one cause of dermal disease. This disease is often ignored in Indonesia because the price of the drug is not affordable by the community. So that garlic should be used as an alternative medicineObjective: This study aims to determine the antibacterial effect of garlic extract (Allium sativum L.) retarding the growth of Staphylococcus epidermidis.Methods: This study is experimental laboratory using plate diffusion method of \"Postest Ony Control Group Design\" design. There are 7 groups, 5 treatment groups and 2 control groups. The concentration of treatment group was 100%, 50%, 25%, 12,5%, 6,25% while for positive control using chloramphenicol and aquadest as negative control. The bacteria used were Staphylococcus epidermidis.Results: The results showed that garlic extract (Allium sativum L.) had an antibacterial effect in inhibiting the growth of Staphylococcus epidermidis. The inhibitory zone concentration in the statistical results shows there are significant differences with values p = 0.000 or p <α.Conclusion: The conclusion of the study showed that Garlic Extract (Allium sativum L.) had an antibacterial effect to retarding the growth of Staphylococcus epidermidis..Keywords: Staphylococcus epidermidis, garlic, antibacteria","PeriodicalId":32099,"journal":{"name":"Eksakta Jurnal IlmuIlmu MIPA","volume":"39 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PENGARUH PEMBERIAN EKSTRAK BAWANG PUTIH (Allium sativum Linn) TERHADAP ZONA HAMBAT PERTUMBUHAN BAKTERI Staphylococcus epidermidis secara in vitro\",\"authors\":\"Akbar Diosasqia Putra\",\"doi\":\"10.33319/AGTEK.V20I1.35\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background:Infectious diseases are the main cause of high morbidity and mortality rates, especially in developing countries such as Indonesia.Indonesia is abundant with plants that can be used as herbal medicine. Garlic is known as having antibacterial elements, one of them is for Staphylococcus epidermidis which is one cause of dermal disease. This disease is often ignored in Indonesia because the price of the drug is not affordable by the community. So that garlic should be used as an alternative medicineObjective: This study aims to determine the antibacterial effect of garlic extract (Allium sativum L.) retarding the growth of Staphylococcus epidermidis.Methods: This study is experimental laboratory using plate diffusion method of \\\"Postest Ony Control Group Design\\\" design. There are 7 groups, 5 treatment groups and 2 control groups. The concentration of treatment group was 100%, 50%, 25%, 12,5%, 6,25% while for positive control using chloramphenicol and aquadest as negative control. The bacteria used were Staphylococcus epidermidis.Results: The results showed that garlic extract (Allium sativum L.) had an antibacterial effect in inhibiting the growth of Staphylococcus epidermidis. The inhibitory zone concentration in the statistical results shows there are significant differences with values p = 0.000 or p <α.Conclusion: The conclusion of the study showed that Garlic Extract (Allium sativum L.) had an antibacterial effect to retarding the growth of Staphylococcus epidermidis..Keywords: Staphylococcus epidermidis, garlic, antibacteria\",\"PeriodicalId\":32099,\"journal\":{\"name\":\"Eksakta Jurnal IlmuIlmu MIPA\",\"volume\":\"39 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-05-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eksakta Jurnal IlmuIlmu MIPA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33319/AGTEK.V20I1.35\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eksakta Jurnal IlmuIlmu MIPA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33319/AGTEK.V20I1.35","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:传染病是高发病率和高死亡率的主要原因,特别是在印度尼西亚等发展中国家。印度尼西亚有丰富的植物可以用作草药。大蒜被认为含有抗菌成分,其中一种是对表皮葡萄球菌有效,表皮葡萄球菌是皮肤疾病的原因之一。这种疾病在印度尼西亚往往被忽视,因为该药的价格是社区负担不起的。目的:研究大蒜提取物(Allium sativum L.)对表皮葡萄球菌生长的抑制作用。方法:本研究在实验室内采用平板扩散法进行“post - only Control Group Design”设计。共7组,5个治疗组,2个对照组。治疗组浓度分别为100%、50%、25%、12%、5%、6%、25%,阳性对照以氯霉素和aquadest为阴性对照。所用细菌为表皮葡萄球菌。结果:大蒜提取物(Allium sativum L.)具有抑制表皮葡萄球菌生长的抗菌作用。统计结果中抑菌带浓度差异有统计学意义(p = 0.000或p <α)。结论:大蒜提取物(Allium sativum L.)具有抑制表皮葡萄球菌生长的抑菌作用。关键词:表皮葡萄球菌;大蒜;抗菌
PENGARUH PEMBERIAN EKSTRAK BAWANG PUTIH (Allium sativum Linn) TERHADAP ZONA HAMBAT PERTUMBUHAN BAKTERI Staphylococcus epidermidis secara in vitro
Background:Infectious diseases are the main cause of high morbidity and mortality rates, especially in developing countries such as Indonesia.Indonesia is abundant with plants that can be used as herbal medicine. Garlic is known as having antibacterial elements, one of them is for Staphylococcus epidermidis which is one cause of dermal disease. This disease is often ignored in Indonesia because the price of the drug is not affordable by the community. So that garlic should be used as an alternative medicineObjective: This study aims to determine the antibacterial effect of garlic extract (Allium sativum L.) retarding the growth of Staphylococcus epidermidis.Methods: This study is experimental laboratory using plate diffusion method of "Postest Ony Control Group Design" design. There are 7 groups, 5 treatment groups and 2 control groups. The concentration of treatment group was 100%, 50%, 25%, 12,5%, 6,25% while for positive control using chloramphenicol and aquadest as negative control. The bacteria used were Staphylococcus epidermidis.Results: The results showed that garlic extract (Allium sativum L.) had an antibacterial effect in inhibiting the growth of Staphylococcus epidermidis. The inhibitory zone concentration in the statistical results shows there are significant differences with values p = 0.000 or p <α.Conclusion: The conclusion of the study showed that Garlic Extract (Allium sativum L.) had an antibacterial effect to retarding the growth of Staphylococcus epidermidis..Keywords: Staphylococcus epidermidis, garlic, antibacteria