希夫碱衍生物在金属离子检测中的医学意义及化学传感应用综述

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Main Group Chemistry Pub Date : 2022-11-23 DOI:10.3233/mgc-220091

Meshal Alshamrani

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引用次数: 0

摘要

希夫碱，以雨果·希夫命名，是伯胺与羰基化合物(醛或酮)在特定条件下反应形成的。希夫碱是一种经济、简单的合成路线，在实验室中很容易获得。它们具有药用和生物应用，如抗病毒、抗氧化、抗真菌、抗癌、驱虫药、抗菌、抗疟疾、抗炎、抗糖化、抗溃疡和镇痛潜力。许多希夫碱被报道用于检测各种金属离子。它们也被用作催化剂、聚合物稳定剂、有机合成的中间体和缓蚀剂。本文综述了近年来生物活性希夫碱衍生物的研究进展及其在金属阳离子检测中的应用。此外，还讨论了用于结构表征的各种光谱技术，如x射线衍射分析(XRD)， FT-IR, UV-vis和核磁共振光谱。

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Medicinal importance and chemosensing applications of Schiff base derivatives for the detection of metal ions: A review

Schiff bases, named after Hugo Schiff, are formed when primary amine reacts with carbonyl compounds (aldehyde or ketone) under specific conditions. Schiff bases are economical, simple synthetic routes, and easily accessible in laboratories. They have medicinal and biological applications such as antiviral, antioxidant, antifungal, anticancer, anthelmintic, antibacterial, antimalarial, anti-inflammatory, antiglycation, anti-ulcerogenic, and analgesic potentials. A number of Schiff bases are reported for the detection of various metal ions. They are also used as catalysts, polymer stabilizers, intermediates in organic synthesis, and corrosion inhibitors. In this review, we have highlighted the recent advancements in the development of bioactive Schiff base derivatives and their sensing applications for detecting metal cations. Additionally, various spectroscopic techniques for structural characterization, such as X-ray diffraction analysis (XRD), FT-IR, UV-vis, and NMR spectroscopy were also discussed.

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来源期刊

Main Group Chemistry 化学-化学综合

CiteScore

2.00

自引率

26.70%

发文量

审稿时长

>12 weeks

期刊介绍： Main Group Chemistry is intended to be a primary resource for all chemistry, engineering, biological, and materials researchers in both academia and in industry with an interest in the elements from the groups 1, 2, 12–18, lanthanides and actinides. The journal is committed to maintaining a high standard for its publications. This will be ensured by a rigorous peer-review process with most articles being reviewed by at least one editorial board member. Additionally, all manuscripts will be proofread and corrected by a dedicated copy editor located at the University of Kentucky.