肥胖患者心血管风险的新生物标志物

A. Berezin
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引用次数: 2

摘要

肥胖仍然是全球心血管(CV)事件和糖尿病的主要原因。虽然肥胖患者至少有两种主要的体型表型(代谢健康和代谢不健康),但这些患者群体的心脏代谢风险差异很大。这篇社论讨论了关于肥胖悖论的争议,以及在心脏代谢风险中对已确定的肥胖患者进行分层的可能性。提示这些生物标志物可以根据肥胖表型预测患者的心血管事件。讨论了代谢生物标志物、祖细胞、利钠肽、炎症细胞因子和半乳糖凝集素-3的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel Biomarkers for Cardiovascular Risk in Obese Patients
Obesity remains a leading cause of cardiovascular (CV) events and diabetes worldwide. Although there are at least two main body-size phenotypes (metabolically healthy and metabolically non-healthy) of individuals with established obesity, the cardiometabolic risk amongst these patients’ populations extremely distinguishes. The editorial is discussed the controversies regarding obese paradox and the probabilities to stratify the patients with established obesity in cardiometabolic risk. It is suggested that the biomarkers could predict CV events in patients depending on obese phenotypes. The role of metabolic biomarkers, progenitor cells, natriuretic peptides, inflammatory cytokines and galectin-3 are discussed.
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