广泛中和HIV-1的IgA和IgG抗体谱系在病毒病毒控制器中的表位收敛

The Tokushima journal of experimental medicine Pub Date : 2022-03-01 DOI:10.1084/jem.20212045

V. Lorin, Ignacio Fernández, Guillemette Masse-Ranson, M. Bouvin-Pley, Luis M Molinos-Albert, C. Planchais, Thierry Hieu, G. Péhau-Arnaudet, D. Hrebík, Giulia Girelli-Zubani, O. Fiquet, F. Guivel-Benhassine, R. Sanders, B. Walker, O. Schwartz, J. Scheid, J. Dimitrov, P. Plevka, M. Braibant, M. Seaman, F. Bontems, J. D. Di Santo, F. Rey, H. Mouquet

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引用次数: 12

摘要

本研究在HIV-1病毒毒控制器中鉴定了三个广泛中和HIV-1的IgA和IgG抗体谱系，它们都针对一个独特的病毒易感部位。

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Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

This study identifies a trio of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a HIV-1 viremic controller that all target a unique viral site of vulnerability.

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The Tokushima journal of experimental medicine

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