抗粘连治疗策略综述

Fitua Al-Saedi
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引用次数: 0

摘要

细菌性疾病是世界范围内死亡率和发病率的重要原因。抗生素使用不当和不加控制是导致细菌对抗生素产生耐药性的原因之一。众所周知,抗生素通过杀死或抑制细菌的生长来阻止细菌感染。抗生素正在干扰对细菌生长至关重要的关键功能。为了克服这个问题,细菌发展出了不同的机制来抵抗抗生素并存活下来。针对细菌的功能而不杀死它们是一种很有前途的抑制细菌感染的方法。细菌附着是导致感染的重要一步。抗黏附治疗的目的是通过干扰细菌附着而不杀死细菌来抑制细菌感染。这篇综述将涵盖抗粘连治疗的不同策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Strategies in anti-adhesion therapy: A review article
Bacterial diseases are an important cause of mortality and morbidity worldwide. The Improper and uncontrolled use of antibiotics contribute to the bacterial resistance to antibiotics. It is well known that the antibiotics stop bacterial infections by killing or   inhibiting their growth. Antibiotics are interfering with critical functions that are important for bacterial growth. To overcome this, bacteria developed different mechanisms to resist the antibiotics and survive.  Targeting bacterial function without killing them is a promising way to inhibit bacterial infection. Bacterial adherence is a serious step towards infection. Anti –adhesion therapy aims to inhibit bacterial infection via interfering with bacterial attachment without killing them. This review will cover different strategies in anti-adhesion therapy.
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