{"title":"大戟植物化学及体外抗癌研究的详细研究","authors":"S. M, Beebi Hazara M, D. P, S. M, A. S, S. Y","doi":"10.46796/ijpc.v3i2.326","DOIUrl":null,"url":null,"abstract":"Health is the main issue of today’s life. Most the diseases are due to improper life style, Taking improper functional foods and by depend on fast, junk foods. Due to these foods, oxidation takes place and oxidation causes lysis of cell and it causes cancer Plants such as Euphorbia heterophylla are commonly found in our surroundings. They are also used for the management of different human diseases. The anticancer activities of leaves from these plants were investigated using aqueous extracts. The extracts are subjected to phytochemical analysis. The invitro methods were used for significant cytotoxicity on Human ovarian cancer cell lines, viz., Pa-1 cells with the IC50 concentrations (The Concentration of the Compound have the capacity to kill 50% of Viable Cells) at 57.08ug/ml respectively after the incubation period of 24hrs. The MTT assay is a colorimetric assay used for the determination of cell proliferation and cytotoxicity, based on reduction of the yellow coloured water soluble tetrazolium dye MTT to formazan crystals. The obtained results suggesting us that the EHE may have effective anticancer potential against the Human ovarian cancer (Pa-1) cells due to its low IC50 value.","PeriodicalId":14190,"journal":{"name":"International Journal of Pharmacognosy and Chemistry","volume":"41 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A detailed study of phytochemical and invitro anticancer study on euphorbia heterophylla .l\",\"authors\":\"S. M, Beebi Hazara M, D. P, S. M, A. S, S. Y\",\"doi\":\"10.46796/ijpc.v3i2.326\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Health is the main issue of today’s life. Most the diseases are due to improper life style, Taking improper functional foods and by depend on fast, junk foods. Due to these foods, oxidation takes place and oxidation causes lysis of cell and it causes cancer Plants such as Euphorbia heterophylla are commonly found in our surroundings. They are also used for the management of different human diseases. The anticancer activities of leaves from these plants were investigated using aqueous extracts. The extracts are subjected to phytochemical analysis. The invitro methods were used for significant cytotoxicity on Human ovarian cancer cell lines, viz., Pa-1 cells with the IC50 concentrations (The Concentration of the Compound have the capacity to kill 50% of Viable Cells) at 57.08ug/ml respectively after the incubation period of 24hrs. The MTT assay is a colorimetric assay used for the determination of cell proliferation and cytotoxicity, based on reduction of the yellow coloured water soluble tetrazolium dye MTT to formazan crystals. The obtained results suggesting us that the EHE may have effective anticancer potential against the Human ovarian cancer (Pa-1) cells due to its low IC50 value.\",\"PeriodicalId\":14190,\"journal\":{\"name\":\"International Journal of Pharmacognosy and Chemistry\",\"volume\":\"41 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pharmacognosy and Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46796/ijpc.v3i2.326\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmacognosy and Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46796/ijpc.v3i2.326","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A detailed study of phytochemical and invitro anticancer study on euphorbia heterophylla .l
Health is the main issue of today’s life. Most the diseases are due to improper life style, Taking improper functional foods and by depend on fast, junk foods. Due to these foods, oxidation takes place and oxidation causes lysis of cell and it causes cancer Plants such as Euphorbia heterophylla are commonly found in our surroundings. They are also used for the management of different human diseases. The anticancer activities of leaves from these plants were investigated using aqueous extracts. The extracts are subjected to phytochemical analysis. The invitro methods were used for significant cytotoxicity on Human ovarian cancer cell lines, viz., Pa-1 cells with the IC50 concentrations (The Concentration of the Compound have the capacity to kill 50% of Viable Cells) at 57.08ug/ml respectively after the incubation period of 24hrs. The MTT assay is a colorimetric assay used for the determination of cell proliferation and cytotoxicity, based on reduction of the yellow coloured water soluble tetrazolium dye MTT to formazan crystals. The obtained results suggesting us that the EHE may have effective anticancer potential against the Human ovarian cancer (Pa-1) cells due to its low IC50 value.