Windows to the Soul- Heterochromia Iridis

Eye colour in humans is a distinct character, and an important trait of an individual’s personality. Heterochromia iridis is a unique phenotype. It is an exceedingly rare condition caused by mutations in genes responsible for synthesis, distribution, and concentration of the melanin pigment in the irises of the eye. Many health disorders and syndromes are associated with heterochromia. Here, we report for the first time in Pakistan, two unique individuals with sectoral heterochromia. This report also addresses the social and psychological pressures these remarkable individuals face in the Pakistani society.