尼日利亚拉各斯沙门氏菌血液感染的流行和抗菌素耐药性。

Q4 Medicine

Infection Epidemiology and Microbiology Pub Date : 2023-03-01 DOI:10.52547/iem.9.1.1

F. Akinkunmi, S. Ajoseh, C. Fakorede, R. Abegunrin, W. Salami, Aminat K. Lawal, K. Akinyemi

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引用次数: 0

摘要

(n=6, 10.91%)， Proteus种(n=13, 23.64%)， Serratia种(n=7, 12.73%)， Citrobacter种(n=2, 3.64%)。本研究采用qPCR和inv A基因引物对阳性血培养样本中沙门氏菌的检出率为100%。分离的沙门氏菌对头孢他啶、头孢噻肟和多利培南的耐药率为100%。沙门氏菌和其他分离菌均存在多药耐药。结论:采用inv A引物对沙门氏菌进行qPCR检测具有较高的特异性。本研究血液病原菌均为耐多药;因此，有必要对医疗环境中的抗生素进行持续评估。对这些细菌分离物进行进一步的分子研究是必要的。

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Prevalence of Salmonella Bloodstream Infection and Antimicrobial Resistance in Lagos, Nigeria.

(n=6, 10.91%), Proteus species (n=13, 23.64%), Serratia species (n=7, 12.73%), and Citrobacter species (n=2, 3.64%). In this study, the detection rate of Salmonella isolates in positive blood culture samples using qPCR and inv A gene primer set was 100%. Salmonella isolates were %100 resistant to ceftazidime, cefotaxime, and doripenem. Multidrug resistance (MDR) was observed in Salmonella and other bacterial isolates. Conclusion: In this study, qPCR using the inv A primer set was found to be highly specific for Salmonella detection. All the bloodstream bacterial pathogens in this study were MDR; thus, there is a need for continuous evaluation of antibiotics in medical settings. Further molecular studies on these bacterial isolates is essential.

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来源期刊

Infection Epidemiology and Microbiology Medicine-Epidemiology

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

6 weeks