圣保罗某公立医院老年人群头颈部非黑色素瘤皮肤癌手术切除分析

Maria Luiza Marinho Vidigal, Nathalia Godoi Ignáciz, Mahmoud Zafer Merhi, Pamela Carrijo Costa, Diego Barão da Silva, Matheus Bartolomei de Siqueira Corradi
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摘要

简介:皮肤癌是世界上最常见的肿瘤之一。它分为两大类:非黑色素瘤皮肤癌(NMSC)和黑色素瘤皮肤癌(MSC),其中NMSC仍分为几个亚型,最常见的是基底细胞癌亚型(BCC),其次是鳞状细胞癌(SCC)。虽然NMSC的死亡率不高,但它在功能、审美和情感层面上的发病率很高。关于老年人(65岁以上)和超级老年患者(80岁开始)的决策,文献存在分歧。目的:本研究旨在:1。老年人面部及颈部NMSC手术切除的并发症分析。证明手术切除可以作为老年人群的一种治疗选择,没有明显更高的发病率风险。方法:这是一项横向、回顾性的单中心定量研究。经研究伦理委员会批准,对2017年8月至2019年11月在Carapicuíba综合医院接受手术的34名患者的电子记录进行了分析。采用定性变量的绝对频率和相对频率对结果进行描述性分析;定量变量采用均值和标准差。通过Fisher’s Exact、Student’s或Mann-Whitney t检验对组间差异进行分析,以评估与手术并发症相关的因素。结果:患者平均年龄85.1岁;女性患病率较高(61.8%);BCC患病率较高(76.5%);高度累及鼻腔(23.5%)、耳周(23.5%)和颧区(17.7%);高血压(55.9%)、糖尿病(35.3%)为主要合并症;术后并发症8例(23.5%),术中并发症0例。结论:手术切除是一种较好的治疗方法。建议治疗选择应个体化,对患者进行整体评估,并考虑年龄组和合并症以外的其他方面。此外,有必要开展新的研究和临床试验与更重要的样本。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of Surgical Resection of Non-Melanoma Skin Cancer in The Head and Neck of Elderly Population in a Public Hospital of São Paulo
Introduction: Skin cancer is among the most frequent neoplasms worldwide. It is divided into two major groups: non-melanoma skin cancer (NMSC) and melanoma skin cancer (MSC), with NMSC still classified into several subtypes, with the most prevalent being basal cell carcinoma subtype (BCC), followed by squamous cell carcinoma (SCC). Although NMSC does not present high mortality rates, it can involve high morbidity on the functional, aesthetic, and emotional levels. There is a divergence in the literature regarding decision-making in the cases of elderly (patients above 65 years of age) and super elderly patients (starting at 80 years of age). Objectives: This study aims to: 1. Identify the complications of surgical resection of the NMSC of the face and neck in the elderly population. 2. Demonstrate that surgical resection can be used as a therapeutic option in the elderly population without a significantly higher risk of morbidities. Method: This is a transversal, retrospective single-center study of quantitative nature. After the approval of the Research Ethics Committees, analysis was performed on the electronic records of 34 patients who underwent surgery at the Carapicuíba General Hospital between August 2017 and November 2019. The descriptive analysis of the results was performed employing absolute and relative frequency of the qualitative variables; mean and standard deviation were used for the quantitative variables. Analysis of group differences was done through the Fisher's Exact, Student's, or Mann-Whitney T-tests, to evaluate the factors associated with the complications of the procedure. Results: The results showed a mean age of 85.1 years; higher prevalence in females (61.8%); higher prevalence of BCC (76.5%); higher involvement in the nasal (23.5%), periauricular (23.5%), and malar regions (17.7%); hypertension (55.9%), and diabetes mellitus (35.3%) as the main comorbidities; 8 (23.5%) patients had post-surgical complications, and 0 patients had intraoperative complications. Conclusion: It was concluded that surgical resection was a good therapeutic method for the patients approached in the study. It is suggested that the therapeutic choice should be individualized, with the evaluation of the patient as a whole and taking into account aspects other than age group and comorbidities. Moreover, it is necessary to develop new studies and clinical trials with a more significant sample.
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