CDPA-1贮藏血对某些血液学指标的影响

N. Almokhtar, N. Ali
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引用次数: 1

摘要

背景:大多数采血袋含有63 mL CPDA抗凝剂,在450 mL±10%的血液中,当血液在2-8°C保存时,CPDA抗凝剂足以抗凝并保证血细胞的活力长达28-35天。血液的长期储存导致细胞血液学上的改变,可能随着时间的推移而失去活力。目的:研究不同贮存时间CPDA-1对血液学指标的影响。材料与方法:研究对象为30名健康志愿献血者。每隔1、7、14、21、28天分析贮藏效果。采用迈达PS 300血液学分析仪测定血液学参数。结果:血红蛋白浓度、堆积细胞体积(pcv %)、MCV显著升高,淋巴细胞、粒细胞和血小板计数降低。结果还显示,总白细胞计数明显下降。结论:枸橼酸磷酸葡萄糖腺嘌呤(CPDA-1)血液参数有退行性改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CDPA-1 Stored Blood Induced Effect on some Haematological Parameters
Background: Most blood collection bags contain 63 mL CPDA anticoagulant which is sufficient to anticoagulant and ensures the viability of blood cells in 450 mL±10% blood for up to 28–35 days when the blood is stored at 2–8°C. Prolonged storage of blood leads to alteration in cells hematologically which may lose viability with time. Aim : The study was conducted to determine the effect of storage on CPDA-1 for varying periods on some hematological parameters. Materials and methods: The study was conducted on blood donated by 30 healthy volunteer donors. Effect of storage was analyzed at 1, 7, 14, 21and 28 days intervals. Hematological parameters were measured using Mindary PS 300 hematology analyzer. Results: There is a highly significant increase in hemoglobin concentration, packed cell volume (P.C.V. %), MCV, and also a decrease in lymphocyte, granulocyte, and platelet count. The results also showed an insignificant decrease in total white blood cell count. Conclusion: There are degenerative changes observed in blood parameters in samples collected in citrate phosphate dextrose adenine (CPDA-1).
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