罗匹尼罗治疗致老年继发性帕金森患者精神错乱、注意力不集中、反应缓慢1例

Emilia Sidharta, Ivon Sindu Wijaya, H. Cahyadi
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引用次数: 0

摘要

背景:罗匹尼罗是一种广泛用于帕金森病或不宁腿综合征(RLS)患者的治疗药物。一些研究期刊表明,长期使用罗匹尼罗会产生副作用。但不幸的是,印度尼西亚没有发表研究表明罗匹尼罗的副作用。目的:报道1例罗匹尼罗治疗引起的多种不良反应。方法:采用时间序列资料收集和纳兰霍量表因果关系分析作为评价方法。结果:本病例报告了一名75岁老年患者服用2毫克罗匹尼罗治疗继发性帕金森病的一些副作用,如精神错乱、注意力难以集中和反应缓慢。在使用罗匹尼罗之前,患者曾使用左旋多巴-苯塞拉肼、三己苯肼和普拉克索治疗帕金森病3年多。在此期间未发生任何副作用。患者给予罗匹尼罗治疗后出现不良反应。使用纳兰霍量表的分析显示,得分为6分,表示可能。结论:本研究的目的是提高卫生工作者,特别是药剂师的认识,以提高长期使用药物的患者(如帕金森病患者)的警觉性。关键词:副作用,继发性帕金森病,罗匹尼罗,老年人
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Confusion, difficulty concentrating, and slow response induced by ropinirole therapy in an elderly patient with secondary Parkinsonism: a case report
Background: Ropinirole is a therapy that is widely used in patients with Parkinson's disease or Restless Leg Syndrome (RLS). Some research journals show that the long-term use of ropinirole can cause side effects. But unfortunately, there are no published studies from Indonesia that show the side effects of ropinirole.. Objective: To report a case of several side effects induced by ropinirole therapy Method : Assessment methods used were time series data collection followed by causality analysis using Naranjo Scale. Results: This case reports several side effects such as confusion, difficulty concentrating, and slow response experienced by a 75-year-old elderly patient who consumed ropinirole 2 mg as a therapy for Secondary Parkinsonism. Before using ropinirole, the patient had used levodopa-benserazide, trihexyphenidyl, and pramipexole to overcome Parkinson's for more than 3 years. During the period no side effects occurred. Side effects occurred after ropinirole therapy was given to patients. The analysis using Naranjo Scale shows a score of 6 which means Probable. Conclusion: The aim of this study is to raise awareness for health workers, especially pharmacists in order to increase alertness in patients using long-term medications such as those with Parkinson's. Keywords: side effect, secondary parkinsonism, ropinirole, elderly
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