Pre-exposure Prophylaxis as HIV Prevention in High Risk Adolescents

A recently published review of the pediatric Human Immunodeficiency Virus (HIV) continuum of care in Pediatric Clinics of North America discussed methods of HIV prevention for children and adolescents1. HIV pre-exposure prophylaxis (PrEP), the use of antiretroviral medications in uninfected persons to prevent HIV infection, was mentioned in the review. The use of PrEP in high risk adolescent populations is an emerging practice. Significant knowledge gaps remain, but the available data to guide current practice is growing due to the vigorous state of PrEP research. A dedicated discussion of PrEP for select adolescents is merited.