某些药物的同分异构体,一种有效,另一种有毒或无效

R. Ayyad, A. Nejm, Ahmed R. Ayyad
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引用次数: 0

摘要

人体的心脏是左旋,胃肠道是右旋,肝脏是左旋。我们食物中的碳水化合物是右旋糖,我们食物中的氨基酸是左旋糖;因此,人类服用的化合物的异构体可能是有害的或无效的。因此,我们将研究一些其中一种异构体有效而另一种无效的药物,如左旋和右旋乙胺丁醇、左旋和右旋多巴、左旋和右旋安非他明、右旋和左旋雷贝拉唑、顺式和反式铂、R和s-己巴比妥、R和s-氟西汀。可能是每一种异构体与另一种异构体有一种药理差异,例如,奎宁和奎尼丁,R和s普罗帕酮。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Isomers of Some Drugs One Effective and the Other Is Toxic or Ineffective
The human body has the heart, which is Levo, and the gastrointestinal tract, with the liver in the Dextro position. The carbohydrates in our food are Dextro, and the amino acids in our food are Levo; hence, the isomers of compounds taken by humans may be harmful or ineffective. As a result, we will investigate some drugs in which one of its isomers is effective while the other is ineffective, such as Levo and Dextro-Ethambutol, Levo and Dextro-Dopa, Levo and Dextro-Amphetamine, Dextro and Levo-Rabeprazole, Cis and Trans-Platin, R and S-Hexobarbital, R and S-Fluoxetine. It may be that each isomer has one pharmacological difference from the other isomer, e.g., quinine and quinidine, and R and S-propafenone.
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