开放窦提术中使用液相浓缩生长因子后骨体积变化的比较研究

Nada Hanafy, nahed abd elmoniem, Hatem H. Al Ahmady
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摘要

目的:探讨液相浓缩生长因子在开放鼻窦提升术中应用后的骨体积变化。材料与方法将12例无牙或部分无牙患者的上颌窦充气后随机分为2组;A组,同种异体骨移植增强双相磷酸钙(BCP)。B组,添加BCP混合液相浓缩生长因子(LPCGF)。采用视觉模拟评分法(VAS)评估疼痛和肿胀。术后即刻及术后6个月采用CBCT测量增骨高度×表面积来评估体积。临床随访时间为术后第1、2天,术后1周。结果12例鼻窦,双侧71.4%,单侧28.5%,女性42.8%,男性57.2%行鼻窦提升术。平均年龄50岁,残骨平均长度7mm。两组创面一期愈合成功率无显著差异,均为71.4%。VAS评分显示,A组肿胀率为42.8%,B组肿胀率为28.5%。疼痛评分逐渐降低,至1周为零。两组比较,体积变化百分比极显著(p=0.004);(A)组为29.31±13.23,(B)组为2.58±1.75。结论:使用LPCG混合BCP骨移植物增加窦内开放性窦内提升术,骨吸收较少,术后6个月骨移植物体积变化百分比低。法典:12/21.10 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.38138.1281口腔医学与外科科学(口腔医学,口腔颌面外科,口腔病理学,口腔生物学)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Volumetric Bone Change After Using Liquid Phase Concentrated Growth Factor in Open Sinus Lift Surgery: A Comparative Study
Purpose: To evaluate of the volumetric bone change after using liquid phase concentrated growth factor in open sinus lift surgery .Material and methods 12 pneumatized maxillary sinuses in edentulous or partially edentulous patients were divided randomly into 2 equal groups; Group (A), augmented by alloplastic bone graft Biphasic Calcium Phosphate (BCP). Group (B), augmented with BCP mixed with liquid phase concentrated growth factor (LPCGF). Visual Analogue Scale (VAS) was used to assess pain and swelling. CBCT was used to assess the volume by measuring height × surface area of augmented bone immediate and 6 months postoperatively. Clinical follow up period was at 1st, 2ndday then, after one week postoperatively. Results 12 sinus , bilateral 71.4%, unilateral 28.5%, female 42.8%, male 57.2% were subjected to sinus lift surgery. Mean age was 50y and average length of residual bone was 7 mm. There was no significant difference between the two groups regarding primary wound healing with percentage of success 71.4%. VAS scale representing swelling of 42.8% in group (A) and 28.5% in group (B). Pain score show decrease gradual till one week to be zero. In comparing between two groups, percentages of change in volume was highly significant (p=0.004) between two groups; in group (A) was 29.31±13.23 while, in group (B) was 2.58±1.75. Conclusion: Use of LPCG mixed with BCP bone graft to augment the sinus with open sinus lift surgery showed less bone resorption as it represented with low percentage of change in bone graft volume at 6 months postoperative . Codex : 12/21.10 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.38138.1281 Oral Medicine & Surgical Sciences (Oral Medicine, Oral & Maxillofacial Surgery, Oral Pathology, Oral Biology)
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