口干会影响终末期肾病患者口腔健康相关的生活质量

L. M. Oliveira, Caroline Schöffer, S. S. Santi, L. C. Argenta, R. Antoniazzi, F. Zanatta
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引用次数: 0

摘要

摘要目的:本双中心横断面研究旨在评估在调整潜在混杂因素后,终末期肾病(ESRD)患者口干症的发生是否与口腔健康相关生活质量(OHRQoL)相关。方法:对180例成人ESRD患者进行口腔检查,检查未经治疗的龋齿、牙周炎和牙齿脱落情况。口干症的存在是通过“你多久感到口腔干燥一次?”这个全球性问题来确定的。通过简化版口腔健康影响概况(OHIP14)问卷评估OHRQoL。采用多变量零膨胀负二项回归分析计算非零评分的发生率比(IRR)和根据暴露的存在对OHIP14评分无影响的优势比(OR)。结果:调整后的模型中,口干症(IRR = 1.57;95% CI: 1.12 ~ 2.20)与较差的OHRQoL相关。调整后的领域特异性分析显示,口干症的发生显著影响心理残疾和社会残疾,而心理不适领域无影响的几率较低(OR = 0.84;95% CI: 0.12 ~ 0.98)。结论:口干对ESRD患者OHRQoL的影响主要体现在心理障碍和社会障碍两方面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Xerostomia impacts oral health-related quality of life in individuals with end-stage renal disease
ABSTRACT Objective: This two-centre cross-sectional study aimed to evaluate whether xerostomia occurrence is associated with oral health-related quality of life (OHRQoL) in patients with end-stage renal disease (ESRD) after the adjustment for potential confounders. Methods: Oral examinations were performed by calibrated examiners for untreated dental caries, periodontitis and tooth loss in 180 adults with ESRD. The presence of xerostomia was determined using the global question “How often does your mouth feel dry?”. OHRQoL was evaluated by the simplified version of the Oral Health Impact Profile (OHIP14) questionnaire. Multivariate zero-inflated negative binomial regression analysis was used to calculate the incidence rate ratios (IRR) for the nonzero scores and odds ratios (OR) of having no impact in OHIP14 scores according to the presence of exposure. Results: In the adjusted model, xerostomia (IRR = 1.57; 95% CI: 1.12 to 2.20) was associated with poorer OHRQoL. The adjusted domain-specific analysis revealed that xerostomia occurrence significantly impacted the psychological disability and social disability, and the chance of having no impact was lower for the psychological discomfort domain (OR = 0.84; 95% CI: 0.12 to 0.98). Conclusion: Xerostomia exert an impact on OHRQoL in patients with ESRD, mainly in the psychological and social disabilities constructs.
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