牛皮癣的合并症

S. Churton, Kristen Doud, N. Korman
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引用次数: 1

摘要

银屑病是一种慢性、免疫介导的炎症性皮肤病,与多种合并症有关,包括银屑病关节炎、心脏代谢疾病、恶性肿瘤、非酒精性脂肪性肝病、自身免疫性疾病、炎症性肠病、阻塞性睡眠呼吸暂停和慢性阻塞性肺病。包括心肌梗死、中风、亚临床动脉粥样硬化在内的心血管疾病,以及肥胖、代谢综合征、糖尿病、高血压和高脂血症,都与牛皮癣有关。共同的炎症通路可能是这些疾病关联的基础,特别是在心血管疾病及其危险因素的情况下。生活质量下降、抑郁、焦虑、吸烟和酗酒也见于牛皮癣患者。认识和理解牛皮癣及其合并症之间的关系对管理牛皮癣患者很重要。银屑病的多重合并症将在此讨论,重点是…
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comorbidities of psoriasis
Psoriasis is a chronic, immune-mediated inflammatory skin disease that is associated with multiple comorbidities including psoriatic arthritis, cardiometabolic diseases, malignancies, nonalcoholic fatty liver disease, autoimmune diseases, inflammatory-bowel disease, obstructive sleep apnea and chronic obstructive pulmonary disease. Cardiovascular disease including myocardial infarction, stroke and subclinical atherosclerosis as well as obesity, metabolic syndrome, diabetes, hypertension and hyperlipidemia, are associated with psoriasis. Shared inflammatory pathways may be the basis for these disease associations, especially in the case of cardiovascular disease and its risk factors. Reduced quality of life, depression, anxiety, smoking and alcoholism are also seen in psoriasis patients. Awareness and understanding of the relationships between psoriasis and its comorbidities is important in managing patients with psoriasis. The multiple comorbidities associated with psoriasis will be discussed here, focusi...
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