重铬酸钾暴露对哺乳期雄性大鼠性器官组织结构的影响

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine Pub Date : 2020-06-03 DOI:10.15835/buasvmcn-vm:2019.0033

J. Savici, D. Brezovan, C. Tulcan, O. Boldura

{"title":"重铬酸钾暴露对哺乳期雄性大鼠性器官组织结构的影响","authors":"J. Savici, D. Brezovan, C. Tulcan, O. Boldura","doi":"10.15835/buasvmcn-vm:2019.0033","DOIUrl":null,"url":null,"abstract":"The aim of this study was the evaluation of integrity biomarkers of reproductive toxicity: histoarchitecture of genital organs (testis and epididymis) and sexual accessory glands (prostate, seminal vesicles and bulbo-urethral glands) at sexual maturity after exposure to potassium dichromate (Cr VI) in suckling period. Consequent to the exposure of male rat pups to hexavalent chromium during suckling period structural changes appeared in genital organs and sexual accessory glands, such as: basal membrane and epithelial disintegration, interstitial edema, wavy basal membrane due to a reduction in tubule diameter, Leydig cell necrosis; epithelial smoothing, epithelial necrosis; epithelial cells desquamation and falling in lumen. Exposure to potassium dichromate (Cr VI) during suckling period produced severe congestive and degenerative lesions in genital organs and sexual accessory glands.","PeriodicalId":9470,"journal":{"name":"Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"The outcome of potassium dichromate exposure on histological structure of male rat sexual organs in suckling period\",\"authors\":\"J. Savici, D. Brezovan, C. Tulcan, O. Boldura\",\"doi\":\"10.15835/buasvmcn-vm:2019.0033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of this study was the evaluation of integrity biomarkers of reproductive toxicity: histoarchitecture of genital organs (testis and epididymis) and sexual accessory glands (prostate, seminal vesicles and bulbo-urethral glands) at sexual maturity after exposure to potassium dichromate (Cr VI) in suckling period. Consequent to the exposure of male rat pups to hexavalent chromium during suckling period structural changes appeared in genital organs and sexual accessory glands, such as: basal membrane and epithelial disintegration, interstitial edema, wavy basal membrane due to a reduction in tubule diameter, Leydig cell necrosis; epithelial smoothing, epithelial necrosis; epithelial cells desquamation and falling in lumen. Exposure to potassium dichromate (Cr VI) during suckling period produced severe congestive and degenerative lesions in genital organs and sexual accessory glands.\",\"PeriodicalId\":9470,\"journal\":{\"name\":\"Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-06-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15835/buasvmcn-vm:2019.0033\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15835/buasvmcn-vm:2019.0033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 2

摘要

本研究的目的是评估生殖毒性的完整性生物标志物:在哺乳期暴露于重铬酸钾(Cr VI)后性成熟时生殖器官(睾丸和附睾)和性腺(前列腺、精囊和球尿道腺)的组织结构。雄性大鼠幼仔在哺乳期暴露于六价铬后，生殖器官和性腺结构发生改变，如:基膜和上皮解体，间质水肿，基膜因小管直径减小而呈波浪状，间质细胞坏死;上皮平滑，上皮坏死;上皮细胞脱屑，落在管腔内。在哺乳期暴露于重铬酸钾(Cr VI)会导致生殖器官和性腺严重的充血性和退行性病变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The outcome of potassium dichromate exposure on histological structure of male rat sexual organs in suckling period

The aim of this study was the evaluation of integrity biomarkers of reproductive toxicity: histoarchitecture of genital organs (testis and epididymis) and sexual accessory glands (prostate, seminal vesicles and bulbo-urethral glands) at sexual maturity after exposure to potassium dichromate (Cr VI) in suckling period. Consequent to the exposure of male rat pups to hexavalent chromium during suckling period structural changes appeared in genital organs and sexual accessory glands, such as: basal membrane and epithelial disintegration, interstitial edema, wavy basal membrane due to a reduction in tubule diameter, Leydig cell necrosis; epithelial smoothing, epithelial necrosis; epithelial cells desquamation and falling in lumen. Exposure to potassium dichromate (Cr VI) during suckling period produced severe congestive and degenerative lesions in genital organs and sexual accessory glands.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine

自引率

0.00%

发文量

审稿时长

4 weeks