海洋来源的药用化合物

K. Pandey, E. Ibezim
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引用次数: 4

摘要

海洋覆盖了地球表面的70%以上,生命起源于海洋,这是一个公认的事实。此外,海洋也是化学上不可模仿的天然产物的来源,这些产物主要积聚在生物体中。从海洋无脊椎动物中分离出了许多具有治疗意义的生物活性化合物,其中一些据报道是微生物来源。其中一些化合物具有药理活性,有助于生物活性化合物的发明和发现,主要用于治疗致命疾病,如癌症、获得性免疫缺陷综合征等,而其他化合物已被开发为镇痛药或治疗炎症等。这些救命药物主要在微生物、藻类和无脊椎动物中大量存在,而在脊椎动物中很少存在。现代技术为从海洋水体中分离生物活性化合物开辟了广阔的研究领域。关键词:化合物,海洋,神奇药物,海洋无脊椎动物,海洋生物多样性医药与相关科学杂志,2010年第7卷第1期
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Medicinal compounds of Marine origin
Oceans cover more than seventy percent of the earth’s surface, and it is a well-acknowledged fact now, that life originated in the oceans. Furthermore, the oceans are also the source of chemically inimitable natural products that are mainly accumulated in living organisms. Numerous bioactive compounds of therapeutic interest have been  isolated from marine invertebrates, and some of them have been reported to be of microbial origin. Several of these compounds show pharmacological activities and are  helpful for the invention and discovery of bioactive compounds, primarily for deadly diseases like cancer, acquired immuno-deficiency syndrome, etc., while other compounds have been developed as analgesics or to treat inflammation, etc. The lifesaving drugs are mainly found abundantly in microorganisms, algae and invertebrates, while they are scarce in vertebrates. Modern technologies have opened enormous areas of research for the isolation of biologically active compounds from marine water bodies. KeyWords: Chemical compounds, seas, wonder drugs, marine invertebrates, oceanic biodiversity Journal of Pharmaceutical and Allied Sciences , Vol. 7 No. 1 (2010)
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