与SARS-CoV-2暂时相关的儿童炎症多系统综合征(PIMS-TS)

Firdaus Abdullah, Ashraf M Shoma, Ahmed Darwish
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摘要

本文将深入研究COVID-19在全球传播后围绕新出现的疾病的知识,它主要影响儿童。PIMS-TS症状与川崎病(KD)重叠,川崎病是一种高炎症和多器官受累的疾病。截至目前,PIMS-TS发病率尚不清楚。尽管对该病知之甚少,但有报道表明该病在KD不常见的地区流行,而以KD闻名的地区没有报告PIMS-TS病例。虽然有些症状与KD重叠,但现在的不同之处在于PIMS-TS影响所有年龄段的儿童,并且症状进展迅速且更严重。多器官受累,如心脏、肾脏、呼吸、血液学、胃肠道、神经病学和皮肤病学,同时伴有高炎症,这表明这种疾病需要在急诊病例中进行治疗。为了治疗PIMS-TS,许多专家通过利用以往KD治疗的成果、成人COVID-19治疗的经验以及其他类型的儿科高炎症治疗,展示了管理该病的步骤。此外,为了防止伴随该综合征的其他并发症,需要通过补充治疗来解决,并且由于该综合征是新发现的,因此必须进行随访。曼苏拉医学杂志(曼苏拉医学院官方杂志)pISSN: 1110-211X;eISSN: 2735 - 3990
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pediatric Inflammatory Multisystem Syndrome, temporally associated with SARS-CoV-2 (PIMS-TS)
This essay will delve into the knowledge circling the new emerging disease after COVID-19 has spread over the whole world and it affects children for the most part. PIMS-TS symptoms overlapped with Kawasaki Disease (KD) which is hyperinflammatory and multiorgan involvement. PIMS-TS incidence is unknown as of date. Albeit little is known about this disease, reports had shown that this disease is prevalent in the region where KD is not a familiar disease while regions that are famous with KD reported no case of PIMS-TS. While some symptoms overlapped with KD, the difference now is PIMS-TS affect the child of all ages and have a quick and more severe progression of symptoms. Multiorgan involvement such as cardiac, renal, respiratory, haematology, gastrointestinal, neurology, and dermatology coincide with hyperinflammation shows that this disease needs to be attended under emergency cases. To treat PIMS-TS, many experts have shown the steps to manage it by using the culmination of previous KD treatment, the experience of adult COVID-19 treatment, and other types of paediatric hyperinflammatory treatment. Also to prevent other complications that accompany the syndrome needs to be addressed with supplementary therapy and follow-up is a compulsory as the syndrome is newly discovered. Mansoura Medical Journal (Official Journal of Mansoura Faculty of Medicine) pISSN: 1110-211X; eISSN: 2735-3990
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