山苍子鲜果精油的化学成分及抗幽门螺杆菌活性研究珀耳斯

IF 2.2 3区农林科学 Q3 CHEMISTRY, APPLIED

Journal of Essential Oil Research Pub Date : 2023-01-22 DOI:10.1080/10412905.2023.2167876

T. T. Hung, L. T. Ngan, Hoang Viet, N. Hoang, T. Hieu

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引用次数: 2

摘要

摘要越南今土省山苍子精油的主要化学成分为天竺葵(32.0%)、将军(24.3%)、香茅醛(14.2%)和柠檬烯(10.1%)。我们鉴定了24个化合物，并与印度、中国和马来西亚报道的24个化合物进行了比较。最低抑菌和杀菌浓度(MIC和MBC)表明，EO对7株幽门螺杆菌具有较高的生长抑制和中等的杀菌活性，其中6株菌株对阿奇霉素、红霉素、左氧氟沙星和甲硝唑等1 ~ 4种抗生素耐药。EO在1/2和3/4×MIC显著抑制了细菌生物膜的形成。EO对幽门螺杆菌脲酶也有抑制作用，可将螺旋形幽门螺杆菌转化为球型幽门螺杆菌。水果EO通过接触和熏蒸作用抑制细菌生长。

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Chemical composition and anti-Helicobacter pylori activity of essential oil from fresh fruits of Litsea cubeba (Lour.) Pers

ABSTRACT Main chemical compositions of essential oil (EO) from Litsea cubeba fruit collected in Kon Tum Province of Vietnam were geranial (32.0%), neral (24.3%), citronellal (14.2%), and limonene (10.1%). Twenty-four compounds of the EO were identified and compared with those from EOs previously reported in India, China, and Malaysia. Minimal inhibitory and bactericidal concentrations (MIC and MBC) indicated that the EO induced high levels of growth inhibition and moderate bactericidal activity against seven test Helicobacter pylori strains, including six strains resistant to one to four antibiotics, azithromycin, erythromycin, levofloxacin, and metronidazole. The bacterial biofilm formation was significantly suppressed by the EO at 1/2 and 3/4×MIC. The EO also exerts inhibitory activity against H. pylori-urease and convert a spiral form of H. pylori into a coccoid form. Fruit EO inhibits bacterial growth via both contact and fumigant action.

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来源期刊

Journal of Essential Oil Research 工程技术-食品科技

CiteScore

6.00

自引率

3.30%

发文量

审稿时长

18-36 weeks

期刊介绍： Journal of Essential Oil Research ( JEOR) is the major forum for the publication of essential oil research and analysis. Each issue includes studies performed on the chemical composition of some of the 20,000 aromatic plants known in the plant kingdom. JEOR is devoted entirely to all phases of research from every corner of the world by the experts in their field. JEOR''s main areas of focus include: -Analytical chemistry- Biological activity- Biotechnology- Chemical composition- Chemical synthesis- Chemosystematics- Microbiological activity- Plant biochemistry/biosynthesis- Toxicology. Published six times per year, JEOR provides articles on the aromatic principles of a plant or its isolates and are directed toward furthering our readers'' knowledge of the aromatic plant and animal kingdoms.