双时双频微波消融套管针的数值分析

Satish Vellavalapalli, R. Repaka
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引用次数: 1

摘要

微波消融(MWA)是一种微创热消融技术,与其他热消融技术相比,具有瘤内温度高、治疗时间短、消融面积大等优点。在MWA过程中获得的消融区域主要取决于所使用的套管针的设计和类型。套管针通过控制组织消融过程中的能量分布在MWA系统中起着至关重要的作用。在这项研究中,一种新的MWA套管针设计被认为可以沿着肿瘤的空间分布实现集中消融区域。双时间套管针每次提供不同频率(2.45 GHz和6 GHz)的能量已被考虑用于肿瘤消融。利用商用有限元软件(COMSOL-Multiphysics)对烧蚀区范围进行了分析。利用了生物热和电磁物理耦合界面。结果表明:所设计的套管针在6 GHz频率下工作,导致了一个直径为3 cm的球形大烧蚀区。在不同频率下,套管针也可以实现不规则形状的消融区域。使用6 GHz频率的套管针完成肿瘤消融所需的最短时间为4分钟,其次是使用2.45 GHz频率的套管针,最短时间为6分钟。所提出的套管针可以成为更好的治疗计划系统(TPS)的一部分,该系统基于肿瘤形状、附近血管的存在以及套管针的精确插入。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microwave Ablation Trocar Operated At Dual Tine Dual-frequency: A Numerical Analysis
Microwave ablation (MWA) is a minimally invasive thermal ablation technique that has the advantages of obtaining high intratumoral temperatures, less treatment time and large ablation region as compared to other thermal ablation techniques. The ablation region obtained during MWA procedure mainly depends on the design and type of the trocar being used. The trocar plays an essential role in the MWA system by governing the energy distribution during tissue ablation. In this study, a novel MWA trocar design has been considered to achieve concentrated ablation region along the tumor's spatial distribution. A dual tine trocar with each tine supplied with energy at different frequencies (2.45 GHz and 6 GHz) has been considered for tumor ablation. Commercially available Finite Element based software has been used (COMSOL-Multiphysics) to analyze the extent of ablation zone. Coupled bioheat and electromagnetic physics interfaces have been utilized. Results showed that the proposed trocar with tines operating at 6 GHz on both the tines leads to a large ablation region (3 cm in diameter) with spherical in shape. Irregularly shaped ablation region can also be achieved by this trocar with tines operating at different frequencies. The minimum time required for complete tumor ablation by the trocar operated at 6 GHz is 4 minutes, followed by 6 minutes for the trocar operated at 2.45 GHz. The proposed trocar can become a part of a better treatment planning system (TPS) based on tumor shape, nearby blood vessel presence, and the trocar's precise insertion.
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