COVID-19幸存者的血浆:对抗大流行冠状病毒的新前沿方法

S. Nimesh, P. Archna
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引用次数: 5

摘要

康复患者的血液可能是抗体的丰富来源,抗体是免疫系统产生的用于攻击病毒的蛋白质。血液中含有抗体的部分,即所谓的恢复期血浆,几十年来一直被用于治疗包括埃博拉和流感在内的传染病。在没有治愈冠状病毒的方法或疫苗的情况下,一群科学家正在一个非常规的地方寻找一种快速的解决方案:康复者的静脉。从本周在纽约市的医院开始,很快在美国的几十个医疗中心,研究人员将开始从COVID-19幸存者身上抽血,他们的身体产生抗体来对抗这种疾病。然后他们将分离血浆,即血液中含有抗体的液体部分。在一个被称为“恢复期血浆治疗”的过程中,他们的抗体将被转移到其他人身上,要么保护他们免受感染,要么增强那些已经生病的人的免疫系统。这种高度实验性的疗法尚未被证明对冠状病毒有效,但中国的初步研究表明,它已经帮助一小部分患者康复。它在过去的传染病爆发中也取得了一些成功,包括抗击导致SARS爆发的冠状病毒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Blood Plasma from Survivors of COVID-19: A Novel and Next Frontier Approach to Fight against Pandemic Coronavirus
Blood from people who have recovered can be a rich source of antibodies, proteins made by the immune system to attack the virus. The part of the blood that contains antibodies, so-called convalescent plasma, has been used for decades to treat infectious diseases, including Ebola and influenza. In the absence of a cure or vaccine for the coronavirus, a group of scientists is searching for a fast solution in an unconventional place: The veins of people who have recovered. Starting in New York City hospitals this week, and soon in dozens of medical centers across the United States, researchers will start drawing blood from COVID-19 survivors, who have antibodies their bodies made to fight the disease. They’ll then isolate their plasma, the liquid part of blood that contains antibodies. And in a process called “convalescent plasma therapy,” their antibodies will be transferred to others, either to protect them against getting infected or to boost the immune systems of those who are already sick. This highly experimental therapy hasn’t been proven to work against the coronavirus, but preliminary research out of China suggests that it has helped a small group of patients recover. It’s also seen some success in past infectious disease outbreaks, including in fighting the coronavirus that caused the SARS outbreak.
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