GtoPdb v.2023.1中的水解酶

Stephen P. H. Alexander, P. Doherty, D. Fairlie, C. Fowler, C. Overall, N. Rawlings, C. Southan, A. Turner
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引用次数: 0

摘要

本节中列出的是《简明指南》其他部分没有积累的水解酶,如单酰基甘油脂肪酶和乙酰胆碱酯酶。胰脂肪酶的主要机制是脂肪消化消化系统;它的抑制作用与脂肪吸收减少有关。CES1在肠道中的含量低于CES2 (P23141),但在肝脏中占主导地位,在肝脏中,它负责许多脂肪族、芳香族和类固醇酯的水解。激素敏感脂肪酶也是一种相对非选择性的酯酶,与类固醇酯水解和甘油三酯代谢有关,特别是在脂肪组织中。内皮脂肪酶由内皮细胞分泌,以高密度脂蛋白调节循环胆固醇。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hydrolases in GtoPdb v.2023.1
Listed in this section are hydrolases not accumulated in other parts of the Concise Guide, such as monoacylglycerol lipase and acetylcholinesterase. Pancreatic lipase is the predominant mechanism of fat digestion in the alimentary system; its inhibition is associated with decreased fat absorption. CES1 is present at lower levels in the gut than CES2 (P23141), but predominates in the liver, where it is responsible for the hydrolysis of many aliphatic, aromatic and steroid esters. Hormone-sensitive lipase is also a relatively non-selective esterase associated with steroid ester hydrolysis and triglyceride metabolism, particularly in adipose tissue. Endothelial lipase is secreted from endothelial cells and regulates circulating cholesterol in high density lipoproteins.
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