职业接触4,4 -亚甲基双(2-氯苯胺)的高毒性和致癌性

Hong-I Chen
{"title":"职业接触4,4 -亚甲基双(2-氯苯胺)的高毒性和致癌性","authors":"Hong-I Chen","doi":"10.4172/2329-6879.1000213","DOIUrl":null,"url":null,"abstract":"4,4 -Methylenebis (2-chloroaniline) (MBOCA) is an aromatic diamine used widely as a curing agent for polyurethane and epoxy resins. The most notable risk factor for the development of lower urinary tract cancers is occupational exposure to aromatic amines, first noted in England in 1895 [1]. A sentinel case of transitional cell carcinoma of the urinary bladder was diagnosed in an MBOCA manufacturing factory in Taiwan in 2005 [2]. There is also no information regarding the daily dose of MBOCA to which workers were exposed or the route of exposure [3]. However, it remains unclear whether MBOCA causes malignancy.","PeriodicalId":19397,"journal":{"name":"Occupational medicine and health affairs","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"High toxicity and carcinogenesis of occupational exposure to 4, 4-methylenebis (2-chloroaniline) (MBOCA)\",\"authors\":\"Hong-I Chen\",\"doi\":\"10.4172/2329-6879.1000213\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"4,4 -Methylenebis (2-chloroaniline) (MBOCA) is an aromatic diamine used widely as a curing agent for polyurethane and epoxy resins. The most notable risk factor for the development of lower urinary tract cancers is occupational exposure to aromatic amines, first noted in England in 1895 [1]. A sentinel case of transitional cell carcinoma of the urinary bladder was diagnosed in an MBOCA manufacturing factory in Taiwan in 2005 [2]. There is also no information regarding the daily dose of MBOCA to which workers were exposed or the route of exposure [3]. However, it remains unclear whether MBOCA causes malignancy.\",\"PeriodicalId\":19397,\"journal\":{\"name\":\"Occupational medicine and health affairs\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Occupational medicine and health affairs\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2329-6879.1000213\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Occupational medicine and health affairs","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2329-6879.1000213","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

4,4 -亚甲基双(2-氯苯胺)(MBOCA)是一种芳香二胺,广泛用作聚氨酯和环氧树脂的固化剂。下尿路癌最显著的风险因素是职业性暴露于芳香胺,1895年首次在英国发现。我们于2005年在台湾一家MBOCA制造工厂诊断出一例膀胱移行细胞癌的前哨病例。也没有关于工人暴露于MBOCA的日剂量或暴露途径的信息。然而,MBOCA是否会导致恶性肿瘤仍不清楚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
High toxicity and carcinogenesis of occupational exposure to 4, 4-methylenebis (2-chloroaniline) (MBOCA)
4,4 -Methylenebis (2-chloroaniline) (MBOCA) is an aromatic diamine used widely as a curing agent for polyurethane and epoxy resins. The most notable risk factor for the development of lower urinary tract cancers is occupational exposure to aromatic amines, first noted in England in 1895 [1]. A sentinel case of transitional cell carcinoma of the urinary bladder was diagnosed in an MBOCA manufacturing factory in Taiwan in 2005 [2]. There is also no information regarding the daily dose of MBOCA to which workers were exposed or the route of exposure [3]. However, it remains unclear whether MBOCA causes malignancy.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信