主成分分析在老年膝关节骨关节炎患者步态运动学中的应用

Renata Noce Kirkwood, R. A. Resende, C. M. B. Magalhães, Henrique de Alencar Gomes, S. A. Mingoti, R. Sampaio
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引用次数: 39

摘要

背景:随着主成分分析(PCA)的引入,步态分析的适用性已经实现,主成分分析是一种统计数据简化技术,允许在个体群体之间比较整个周期。目的:应用PCA,比较一组患有和未诊断为早期和中度骨关节炎(OA)的老年妇女在步态中膝关节的运动学,在额骨和矢状面。方法:38例老年女性膝关节OA患者(69.6±8.1岁)和40例无症状患者(70.3±7.7岁)参加本研究。运动学分析采用Qualisys Pro-reflex系统。结果:OA组患者步速和步长明显降低(p<0.05), WOMAC疼痛评分较高。额平面各成分组间差异无统计学意义。在矢状面,三个主成分解释了99.7%的数据方差。判别分析表明,成分2和成分3的分类正确率为71.8%。然而,CP3是组间判别力较高的变量,它捕捉了步态中膝关节屈曲角度的大小差异。结论:PCA是一种有效的多变量统计技术,可以分析步态周期内的运动步态波形。OA组膝关节屈曲角度较小被认为是组间的区别因素,因此在老年女性膝关节OA的物理治疗评价和治疗中应予以考虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aplicação da análise de componentes principais na cinemática da marcha de idosas com osteoartrite de joelho
BACKGROUND: The applicability of gait analysis has been implemented with the introduction of the principal component analysis (PCA), a statistical data reduction technique that allows the comparison of the whole cycle between groups of individuals. OBJECTIVES: Applying PCA, to compare the kinematics of the knee joint during gait, in the frontal and sagittal planes, between a group of elderly women with and without diagnosis in the initial and moderate stages of Osteoarthritis (OA). METHODS: A total of 38 elderly women (69.6±8.1 years) with knee OA and 40 asymptomatic (70.3±7.7 years) participated on this study. The kinematics was obtained using the Qualisys Pro-reflex system. RESULTS: The OA group showed decreased gait velocity and stride length (p<0.05) and was characterized with higher WOMAC pain score. In the frontal plane, the between-group differences of the components were not significant. In the sagittal plane, three principal components explained 99.7% of the data variance. Discriminant analysis indicated that component 2 and 3 could classify correctly 71.8% of the individuals. However, CP3, which captures the difference in the flexion knee angle magnitude during gait, was the variable with higher discrimination power between groups. CONCLUSIONS: PCA is an effective multivariate statistical technique to analyse the kinematic gait waveform during the gait cycle. The smaller knee flexion angle in the OA group was appointed as a discriminatory factor between groups, therefore, it should be considered in the physical therapy evaluation and treatment of elderly women with knee OA.
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