溶性胰岛素注射液中间甲酚含量测定方法的建立

M. Jalilov, Zulaykho Sumanova, Nigora Kutlimuratona
{"title":"溶性胰岛素注射液中间甲酚含量测定方法的建立","authors":"M. Jalilov, Zulaykho Sumanova, Nigora Kutlimuratona","doi":"10.32743/unichem.2021.89.11.12483","DOIUrl":null,"url":null,"abstract":"This article presents the results of the development of a methodic for the determination of metacresol in a medicinal product of dissolved injectable insulin. The choice of the reagent for the complexation reaction, finding the λ maximum of the complex of the reagent (FeCl3) with m-cresol, the effect of pH on the analytical signal was studied. The straightness of the optical density in the determination of m-cresol in the concentration range of 0.625–12.5 mg / 8 ml with a correlation coefficient (R2) of 0.981 at λ max 567 nm has been proved. Ключевые слова: м-крезол, инсулин,","PeriodicalId":23473,"journal":{"name":"Universum:Chemistry & biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"DEVELOPMENT OF A METHOD FOR DETERMINATION OF M-CRESOL IN A DRUG OF DISSOLVED INJECTION INSULIN\",\"authors\":\"M. Jalilov, Zulaykho Sumanova, Nigora Kutlimuratona\",\"doi\":\"10.32743/unichem.2021.89.11.12483\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This article presents the results of the development of a methodic for the determination of metacresol in a medicinal product of dissolved injectable insulin. The choice of the reagent for the complexation reaction, finding the λ maximum of the complex of the reagent (FeCl3) with m-cresol, the effect of pH on the analytical signal was studied. The straightness of the optical density in the determination of m-cresol in the concentration range of 0.625–12.5 mg / 8 ml with a correlation coefficient (R2) of 0.981 at λ max 567 nm has been proved. Ключевые слова: м-крезол, инсулин,\",\"PeriodicalId\":23473,\"journal\":{\"name\":\"Universum:Chemistry & biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Universum:Chemistry & biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32743/unichem.2021.89.11.12483\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Universum:Chemistry & biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32743/unichem.2021.89.11.12483","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

本文介绍了溶性注射胰岛素制剂中甲克雷醇含量测定方法的发展结果。络合反应试剂的选择,确定了FeCl3与间甲酚络合物的λ最大值,研究了pH对分析信号的影响。在0.625 ~ 12.5 mg / 8 ml浓度范围内测定间甲酚的光密度具有直线性,在λ max 567 nm处相关系数(R2)为0.981。Ключевые слова: -крезол, инсулин,
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DEVELOPMENT OF A METHOD FOR DETERMINATION OF M-CRESOL IN A DRUG OF DISSOLVED INJECTION INSULIN
This article presents the results of the development of a methodic for the determination of metacresol in a medicinal product of dissolved injectable insulin. The choice of the reagent for the complexation reaction, finding the λ maximum of the complex of the reagent (FeCl3) with m-cresol, the effect of pH on the analytical signal was studied. The straightness of the optical density in the determination of m-cresol in the concentration range of 0.625–12.5 mg / 8 ml with a correlation coefficient (R2) of 0.981 at λ max 567 nm has been proved. Ключевые слова: м-крезол, инсулин,
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信