BioLEIR的可行性研究

S. Ghithan, G. Roy, S. Schuh
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引用次数: 3

摘要

生物医学界要求欧洲核子研究中心调查将低能量离子环(LEIR)加速器转变为多学科生物医学研究设施(BioLEIR)的可能性,该设施可以提供充足、高质量的一系列光离子光束,适用于临床导向的细胞培养基础研究和辐射仪器开发。BioLEIR将在LEIR不为欧洲核子研究中心物理项目提供重离子时运行。该研究小组的任务是根据以往的经验,利用高水平的工程估算,编写一份可行性研究报告,目的是:-与欧洲核子研究中心医学应用国际战略委员会密切合作,从生物医学界收集对这种设施的需求;-根据要求确定一套连贯的光束参数;-探索从源头到生物医学终端站,整个设施是否能满足光束要求;-考虑到欧洲核子研究中心的整体时间表和计划,对设施进行可行性研究;-使设施设计简单而坚固,同时尽量减少维修和操作的成本;-建立项目执行所需材料和人员的高水平成本计算;-描述理想的安装方案;-对项目进行高层次的风险分析;-确定可能有困难的范畴,以及如果研究进行并成为项目,所需的研发工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feasibility Study for BioLEIR
The biomedical community asked CERN to investigate the possibility to transform the Low Energy Ion Ring (LEIR) accelerator into a multidisciplinary, biomedical research facility (BioLEIR) that could provide ample, high-quality beams of a range of light ions suitable for clinically oriented fundamental research on cell cultures and for radiation instrumentation development. BioLEIR would be operated when LEIR is not providing heavy ions for the CERN physics programme. The study group was mandated to write a Feasibility Study Report, using high-level engineering estimates based on previous experience, with the aim to: - collect the requirements for such a facility from the biomedical community in close collaboration with the International Strategy Committee for CERN Medical Applications; - determine a coherent set of beam parameters, based on the requirements; - explore whether the beam requirements can be met throughout the facility, from the source to the biomedical end-stations; - perform a feasibility study of the facility, taking into consideration the overall CERN schedules and programmes; - favour simplicity and robustness of the facility design, while minimizing the cost of maintenance and operation; - establish a high-level costing of material and personnel needed for project implementation; - describe the preferred installation scenario; - perform a high-level risk analysis for the project; - identify the areas of potential difficulty, and the required R&D should the study go ahead and become a project.
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