群体内婚水平分析是群体遗传学和医学遗传学研究的基础

Sergei N. Sokorev, O. Efremova, I. Sorokina
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引用次数: 1

摘要

背景:在进行群体遗传学和遗传流行病学研究时,应考虑到内婚制指数,以评估基本人口的水平、人口迁移活动的特征和人口的隔离程度。该研究的目的是:评估现代别尔哥罗德地区整个人口的内婚制水平。材料与方法:基于别尔哥罗德州登记办公室2016-2018年的11052份婚姻记录,对别尔哥罗德州21个区所有行政单位的全体人口进行内婚制指数研究。内婚制指数是根据配偶出生地的数据计算的,即在一定人口中出生的丈夫和妻子的比例。结果:别尔哥罗德地区人口的区级内婚制指数变化范围为0.33 ~ 0.68,区域平均值为0.46,处于该指标在俄罗斯联邦俄罗斯人口中的变异性范围内。目前,包括大城市和大城市在内的区域人口的内婚制在农村人口中超过了这一指标。对于该地区高度城市化的地区,基础人口的规模与该地区的行政边界相对应,而对于农村人口,基础人口的规模超过了该地区的行政边界。应当指出,农村人口这一指标的降低值符合一般移徙趋势。别尔哥罗德州区域人口中移民流入的增加导致内婚制指数下降,三个时期(1990年、2000年和2019年)每1000名居民的移民人数与内婚制指数之间已确立的负相关关系证明了这一点。结论:别尔哥罗德地区人口的特点是高迁移活动,这导致人口中的内婚制水平下降。目前,别尔哥罗德地区的初级人口规模与该地区相当或略高于该地区。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of the level of population endogamia as the basis of population-genetic and medical-genetic studies
Background: When conducting population-genetic and genetic-epidemiological studies, the endogamy index should be taken into account to assess the level of the elementary population, characteristics of the migration activity of the population and the degree of isolation of the population. The aim of the study: To assess the level of endogamy among the entire population of the Belgorod region in the modern period of time. Materials and methods: Based on 11052 marriage records of the Registry Office in the Belgorod region for 2016-2018, the endogamy index was studied among the entire population in all administrative units of the Belgorod region – 21 districts. The endogamy index was calculated on the basis of data on the place of birth of spouses, as the proportion of husbands and wives born in a given population. Results: It was found that in the district populations of the Belgorod region, the endogamy index at the district level varied from 0.33 to 0.68 with an average value for the region of 0.46, which is within the range of variability of this indicator among the Russian populations of the Russian Federation. At present, the endogamy of regional populations, which include big and large cities, exceeds this indicator among the rural population. For highly urbanized districts of the region, the size of the elementary population corresponds to the administrative boundaries of the district, while for the rural population, the size of the elementary population exceeds the boundaries of the district. It should be noted that the reduced values of this indicator for the rural population correspond to general migration trends. An increase in the inflow of migrants to the regional populations of the Belgorod region leads to a decrease in the endogamy index, as evidenced by the established inverse correlations between the number of migrants per 1000 inhabitants over three time periods (1990, 2000, and 2019) and the endogamy index. Conclusion: The populations of the Belgorod region are characterized by high migration activity, which leads to a decrease in the level of endogamy among the population. At present, the size of the elementary population in the Belgorod region corresponds to the area or slightly exceeds it.
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