关于撤销全氟辛烷磺酸(PFOA)水生预测无效应浓度(PNEC)衍生的通知

Wang Ying, J. Mu, Juying Wang
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引用次数: 2

摘要

全氟辛酸(PFOA)是一种具有代表性的全氟表面活性剂,存在于各种环境基质中。人们对其对水生生态系统的安全阈值知之甚少。PFOA的预测无效应浓度(PNECs)是根据测量/预测的慢性/急性毒性数据得出的。应用种间相关估计(ICE)程序和最终急慢性比(FACR)来研究它们推导PNEC的能力。推荐的PFOA水生毒性阈值范围为0.30 ~ 8.48 mg/L。基于ice的物种敏感性分布(SSD)方法对PNEC的推导具有一定的潜力,特别是在毒性数据有限的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Notice of RetractionAquatic Predicted No-Effect Concentration (PNEC) Derivation for Perfluorooctane Sulfonic Acid (PFOA)
Perfluorooctanoic acid (PFOA), the representative perfluorinated surfactant, is an anthropogenic pollutant detected in various environmental matrices. Little is known regarding its safe thresholds to the aquatic ecosystem. Predicted no-effect concentrations (PNECs) for PFOA were derived based on the measured/predicted chronic/acute toxicity data. The interspecies correlation estimation (ICE) program and final acute-to-chronic ratio (FACR) were applied to investigate their capability for the derivation of PNEC. The recommended aquatic toxicity thresholds for PFOA are in the range of 0.30 ~ 8.48 mg/L. The ICE-based species sensitivity distribution (SSD) method has certain potential for the derivation of PNEC especially when toxicity data are limited.
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