{"title":"青年人皮下肺气肿合并纵隔气肿和气腹的罕见病因:百草枯中毒","authors":"P. Upadhya, S. C., A. Moorthy, B. N, M. R., J. B","doi":"10.18231/j.ijirm.2022.009","DOIUrl":null,"url":null,"abstract":"Paraquat is a rapid-acting herbicide widely used in many parts of the world. Although it is considered safe when exposed to the body surface, ingestion of this substance is highly fatal. Organ damage is caused by the production of free radicals and the depletion of nicotinamide adenine dinucleotide phosphate (NADPH). Multiple organs are involved in the damage, particularly organs requiring high blood flow like lungs, heart, kidneys, and liver. There is no proven effective antidote for the poisoning, and it is nearly 100% fatal. Here, we report an 18 years old young male presenting with pneumo-mediastinum, subcutaneous emphysema with pneumo-peritoneum after paraquat ingestion, which is a rare presentation of paraquat poisoning.","PeriodicalId":14503,"journal":{"name":"IP Indian Journal of Immunology and Respiratory Medicine","volume":"114 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A rare cause of subcutaneous emphysema with pneumomediastinum and pneumoperitoneum in a young adult: Paraquat poisoning\",\"authors\":\"P. Upadhya, S. C., A. Moorthy, B. N, M. R., J. B\",\"doi\":\"10.18231/j.ijirm.2022.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Paraquat is a rapid-acting herbicide widely used in many parts of the world. Although it is considered safe when exposed to the body surface, ingestion of this substance is highly fatal. Organ damage is caused by the production of free radicals and the depletion of nicotinamide adenine dinucleotide phosphate (NADPH). Multiple organs are involved in the damage, particularly organs requiring high blood flow like lungs, heart, kidneys, and liver. There is no proven effective antidote for the poisoning, and it is nearly 100% fatal. Here, we report an 18 years old young male presenting with pneumo-mediastinum, subcutaneous emphysema with pneumo-peritoneum after paraquat ingestion, which is a rare presentation of paraquat poisoning.\",\"PeriodicalId\":14503,\"journal\":{\"name\":\"IP Indian Journal of Immunology and Respiratory Medicine\",\"volume\":\"114 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IP Indian Journal of Immunology and Respiratory Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijirm.2022.009\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IP Indian Journal of Immunology and Respiratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijirm.2022.009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A rare cause of subcutaneous emphysema with pneumomediastinum and pneumoperitoneum in a young adult: Paraquat poisoning
Paraquat is a rapid-acting herbicide widely used in many parts of the world. Although it is considered safe when exposed to the body surface, ingestion of this substance is highly fatal. Organ damage is caused by the production of free radicals and the depletion of nicotinamide adenine dinucleotide phosphate (NADPH). Multiple organs are involved in the damage, particularly organs requiring high blood flow like lungs, heart, kidneys, and liver. There is no proven effective antidote for the poisoning, and it is nearly 100% fatal. Here, we report an 18 years old young male presenting with pneumo-mediastinum, subcutaneous emphysema with pneumo-peritoneum after paraquat ingestion, which is a rare presentation of paraquat poisoning.