Fe3O4@SiO2@D-NHCS-Tr在无溶剂条件下多组分反应合成吲哚-3-酰基- 4h -铬烯的高效可重复使用催化剂

Organic Chemistry eJournal Pub Date : 2020-01-01 DOI:10.2139/ssrn.3745219

R. Baharfar, Sahar Peiman, B. Maleki

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引用次数: 2

摘要

在无溶剂条件下，以fe3o4 @ sio2 @D-NHCS-Tr为有效催化剂，在吲哚衍生物、水杨醛和活性亚甲基化合物的三组分反应中合成了吲哚-3-yl-4 H -铬衍生物。该方法具有反应条件绿色、分离容易、催化剂生态友好、成本效益高、反应时间短、产率高等特点

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Fe3O4@SiO2@D-NHCS-Tr as Efficient and Reusable Catalyst for the Synthesis of indol-3-yl-4H-chromene via a Multi-Component Reaction Under Solvent-Free Conditions

Fe 3 O 4 @SiO 2 @D-NHCS-Tr was used as an efficient catalyst in the three-component reaction between indole derivatives , salicylaldehyde and active methylene compounds under solvent-free conditions to the synthesis of indol-3-yl-4 H -chromene derivatives. The features of this method include the green conditions of the reaction, easy separation, eco-friendly and cost-effectiveness of the catalyst, and high yield in short reaction times

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Organic Chemistry eJournal

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