Liying Jiang, Xianbo Luo, Qing Tian, Hui Wang, Xinxia Cai
{"title":"一次性生物传感器测定全血血红蛋白","authors":"Liying Jiang, Xianbo Luo, Qing Tian, Hui Wang, Xinxia Cai","doi":"10.1109/NEMS.2006.334687","DOIUrl":null,"url":null,"abstract":"A disposable biosensor for the determination of hemoglobin in whole blood is described. The sensing method is based on amperometric detection technology. Platinized thin-film gold electrode is employed as a base electrode for the immobilization of mediator potassium ferricyanide. Saponin hemolyses the erythrocytes and hemoglobin is released. The biosensor has characters of rapid response time (60 s), high accuracy (> 90%), small sample volume (3 muL) and good precision (CV = 3.6%). The biosensor connected with the homemade portable meter can be used to determine hemoglobin concentration in clinical diagnosis and home-care purpose for athletes and patients potentially","PeriodicalId":6362,"journal":{"name":"2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"147 1","pages":"204-208"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Disposable Biosensor for Hemoglobin Determination in Whole Blood\",\"authors\":\"Liying Jiang, Xianbo Luo, Qing Tian, Hui Wang, Xinxia Cai\",\"doi\":\"10.1109/NEMS.2006.334687\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A disposable biosensor for the determination of hemoglobin in whole blood is described. The sensing method is based on amperometric detection technology. Platinized thin-film gold electrode is employed as a base electrode for the immobilization of mediator potassium ferricyanide. Saponin hemolyses the erythrocytes and hemoglobin is released. The biosensor has characters of rapid response time (60 s), high accuracy (> 90%), small sample volume (3 muL) and good precision (CV = 3.6%). The biosensor connected with the homemade portable meter can be used to determine hemoglobin concentration in clinical diagnosis and home-care purpose for athletes and patients potentially\",\"PeriodicalId\":6362,\"journal\":{\"name\":\"2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems\",\"volume\":\"147 1\",\"pages\":\"204-208\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/NEMS.2006.334687\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NEMS.2006.334687","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Disposable Biosensor for Hemoglobin Determination in Whole Blood
A disposable biosensor for the determination of hemoglobin in whole blood is described. The sensing method is based on amperometric detection technology. Platinized thin-film gold electrode is employed as a base electrode for the immobilization of mediator potassium ferricyanide. Saponin hemolyses the erythrocytes and hemoglobin is released. The biosensor has characters of rapid response time (60 s), high accuracy (> 90%), small sample volume (3 muL) and good precision (CV = 3.6%). The biosensor connected with the homemade portable meter can be used to determine hemoglobin concentration in clinical diagnosis and home-care purpose for athletes and patients potentially