{"title":"UJI KANDUNGAN HIDROQUINON PADA SEDIAAN KRIM RACIKAN DOKTER DAN KRIM PENCERAH WAJAH DENGAN MENGGUNAKAN SPEKTROFOTOMETER UV","authors":"R. Yuan","doi":"10.30651/jmlt.v4i1.6949","DOIUrl":null,"url":null,"abstract":"Hydroquinon is a chemical used as a skin lightener. However, its effectiveness began to be questioned after the emergence of a study showing that hydroquinone can trigger cancer. This study aims to analyze the hydroquinone content of several doctor-made creams and branded facial lightening creams circulating in Denpasar. This research is an experimental research. The sample used consisted of five samples of doctor-made creams coded D1-D5, while branded lightening creams were coded P1-P10. Based on the results of the analysis, the wavelength of 293 nm is the wavelength that provides maximum absorption with the equation y = 0.023x + 0.005 with a value of R2 = 0.996. 0.023. The results of the analysis showed that all samples of the doctor's cream contained hydroquinone with an average of 11.9322 ppm or 1.1932% and did not exceed the BPOM regulations, namely 5% for cream preparations prescribed by doctors. And all samples of branded facial lightening creams in Denpasar City contain hydroquinone with an average hydroquinone level of 3,987 ppm or 0.3987% and do not exceed the BPOM regulations, which is 2% for whitening cream preparations that are sold freely without a doctor's prescription.","PeriodicalId":22695,"journal":{"name":"THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST","volume":"27 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30651/jmlt.v4i1.6949","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
UJI KANDUNGAN HIDROQUINON PADA SEDIAAN KRIM RACIKAN DOKTER DAN KRIM PENCERAH WAJAH DENGAN MENGGUNAKAN SPEKTROFOTOMETER UV
Hydroquinon is a chemical used as a skin lightener. However, its effectiveness began to be questioned after the emergence of a study showing that hydroquinone can trigger cancer. This study aims to analyze the hydroquinone content of several doctor-made creams and branded facial lightening creams circulating in Denpasar. This research is an experimental research. The sample used consisted of five samples of doctor-made creams coded D1-D5, while branded lightening creams were coded P1-P10. Based on the results of the analysis, the wavelength of 293 nm is the wavelength that provides maximum absorption with the equation y = 0.023x + 0.005 with a value of R2 = 0.996. 0.023. The results of the analysis showed that all samples of the doctor's cream contained hydroquinone with an average of 11.9322 ppm or 1.1932% and did not exceed the BPOM regulations, namely 5% for cream preparations prescribed by doctors. And all samples of branded facial lightening creams in Denpasar City contain hydroquinone with an average hydroquinone level of 3,987 ppm or 0.3987% and do not exceed the BPOM regulations, which is 2% for whitening cream preparations that are sold freely without a doctor's prescription.