Qiangcai Mai, Lihua Qan, Guosheng Su, Miaoling Liang, Xiaoye Su, Y. Gan, Qinglu Li, Cangrui Long, Huayan Zhu, Qiaocui Jiang, Yanling Zheng, Jie He, Tianwu Liang, Jing Li, Buqing Su
{"title":"CG与TBA联合检测在肝胆系统疾病鉴别诊断中的临床应用价值","authors":"Qiangcai Mai, Lihua Qan, Guosheng Su, Miaoling Liang, Xiaoye Su, Y. Gan, Qinglu Li, Cangrui Long, Huayan Zhu, Qiaocui Jiang, Yanling Zheng, Jie He, Tianwu Liang, Jing Li, Buqing Su","doi":"10.4236/ns.2022.142008","DOIUrl":null,"url":null,"abstract":"Objective: To understand the clinical value of combined detection of cholyglycine CG and TBA in differential diagnosis of hepatobiliary diseases. Methods: Serum samples from 50 healthy people were collected as healthy control group. According to the latest disease diagnosis and treatment plan, 58 cases of HBV asymptomatic carrier group, 17 cases of viral hepatitis group, 49 cases of cirrhosis group, 50 cases of primary liver cancer group and 50 cases of other hepatobiliary diseases groups were collected respectively. The concentration levels of cholyglycine and total bile acid in each group were detected, and the differences among each group were compared. Results: By statistical analysis, serum CG concentration in viral hepatitis group, cirrhosis group, primary liver cancer group and other hepatobiliary diseases group was significantly higher than that in asymptomatic HEPATITIS B carriers and healthy control group, the differences were statistically significant (p < 0.05). While, the serum CG concentration of asymptomatic hepatitis B virus carrier group was similar to that of healthy control group, the difference was not statistically significant (p > 0.05). There was","PeriodicalId":19083,"journal":{"name":"Natural Science","volume":"25 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical Application Value of Combined Detection of CG and TBA in Differential Diagnosis of Hepatobiliary System Diseases\",\"authors\":\"Qiangcai Mai, Lihua Qan, Guosheng Su, Miaoling Liang, Xiaoye Su, Y. Gan, Qinglu Li, Cangrui Long, Huayan Zhu, Qiaocui Jiang, Yanling Zheng, Jie He, Tianwu Liang, Jing Li, Buqing Su\",\"doi\":\"10.4236/ns.2022.142008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To understand the clinical value of combined detection of cholyglycine CG and TBA in differential diagnosis of hepatobiliary diseases. Methods: Serum samples from 50 healthy people were collected as healthy control group. According to the latest disease diagnosis and treatment plan, 58 cases of HBV asymptomatic carrier group, 17 cases of viral hepatitis group, 49 cases of cirrhosis group, 50 cases of primary liver cancer group and 50 cases of other hepatobiliary diseases groups were collected respectively. The concentration levels of cholyglycine and total bile acid in each group were detected, and the differences among each group were compared. Results: By statistical analysis, serum CG concentration in viral hepatitis group, cirrhosis group, primary liver cancer group and other hepatobiliary diseases group was significantly higher than that in asymptomatic HEPATITIS B carriers and healthy control group, the differences were statistically significant (p < 0.05). While, the serum CG concentration of asymptomatic hepatitis B virus carrier group was similar to that of healthy control group, the difference was not statistically significant (p > 0.05). There was\",\"PeriodicalId\":19083,\"journal\":{\"name\":\"Natural Science\",\"volume\":\"25 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4236/ns.2022.142008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4236/ns.2022.142008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Clinical Application Value of Combined Detection of CG and TBA in Differential Diagnosis of Hepatobiliary System Diseases
Objective: To understand the clinical value of combined detection of cholyglycine CG and TBA in differential diagnosis of hepatobiliary diseases. Methods: Serum samples from 50 healthy people were collected as healthy control group. According to the latest disease diagnosis and treatment plan, 58 cases of HBV asymptomatic carrier group, 17 cases of viral hepatitis group, 49 cases of cirrhosis group, 50 cases of primary liver cancer group and 50 cases of other hepatobiliary diseases groups were collected respectively. The concentration levels of cholyglycine and total bile acid in each group were detected, and the differences among each group were compared. Results: By statistical analysis, serum CG concentration in viral hepatitis group, cirrhosis group, primary liver cancer group and other hepatobiliary diseases group was significantly higher than that in asymptomatic HEPATITIS B carriers and healthy control group, the differences were statistically significant (p < 0.05). While, the serum CG concentration of asymptomatic hepatitis B virus carrier group was similar to that of healthy control group, the difference was not statistically significant (p > 0.05). There was
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