可折叠不对称动脉狭窄模型的血流和压缩

Shunichi Kobayashi, Takeshi Horie, Tomohito Amaya, H. Morikawa, D. Tang, D. Ku
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引用次数: 0

摘要

血流通过严重狭窄的狭窄区域类似于通过文丘里管或流量喷嘴。在收缩段,血液可以加速到高速。在这种情况下,外部压力可能大于内部流体压力,动脉可能塌陷。这种塌陷可能在动脉粥样硬化斑块断裂的发展和随后的血栓形成或远端栓塞中起重要作用[1,2]。我们使用了一个不对称的实验模型,该模型非常接近动脉疾病的情况,即整个狭窄是柔顺的,狭窄壁没有受到刚性约束。本研究旨在探讨在稳定流动条件下,流量、压力与致溃狭窄偏心率之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Flow and Compression in Collapsible Asymmetric Stenosis Models of Arterial Disease
Blood flow through the constricted area of a severe stenosis is similar to that through a venturi or flow nozzle. In the contraction section, the blood can accelerate to high speed. In this situation, the external pressure may be greater than the internal fluid pressure, and the artery could collapse. This collapse may be important in the development of atherosclerotic plaque fracture and subsequent thrombosis or distal embolization [1,2]. We used an asymmetric experimental model that closely approximates the arterial disease situation where the entire stenosis is compliant and the stenosis wall was not rigidly constrained. This study was to examine the relationships between flow rate, pressure and eccentricity of the stenosis inducing collapse under steady flow.
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