TP-5及其类似物对小鼠皮肤移植的影响。

Journal of immunopharmacology Pub Date : 1985-01-01 DOI:10.3109/08923978509026470

B. Szende, L. Kisfaludy, K. Lapis, L. Dénes, L. Szporny, O. Nyéke, I. Schön, G. Hajos, J. Ember, M. Constantin

{"title":"TP-5及其类似物对小鼠皮肤移植的影响。","authors":"B. Szende, L. Kisfaludy, K. Lapis, L. Dénes, L. Szporny, O. Nyéke, I. Schön, G. Hajos, J. Ember, M. Constantin","doi":"10.3109/08923978509026470","DOIUrl":null,"url":null,"abstract":"The immunostimulatory action of oligopeptides RGH-0205 (Arg-Lys-Asp), RGH-0206 (Arg-Lys-Asp-Val) and TP-5 (Arg-Lys-Asp-Val-Try) was measured using the B10LP to C57BL skin graft system and the determination of splenic T cell ratio. While thymectomy increased the period between skin grafting and rejection, each of the oligopeptides increased the number of splenic T cells and in some extent restored the rejection capacity of thymectomised C57Bl mice, presumably by restoration of thymic hormone function.","PeriodicalId":16049,"journal":{"name":"Journal of immunopharmacology","volume":"125 1","pages":"67-78"},"PeriodicalIF":0.0000,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"The effect of TP-5 and its analogs on skin grafts in mice.\",\"authors\":\"B. Szende, L. Kisfaludy, K. Lapis, L. Dénes, L. Szporny, O. Nyéke, I. Schön, G. Hajos, J. Ember, M. Constantin\",\"doi\":\"10.3109/08923978509026470\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The immunostimulatory action of oligopeptides RGH-0205 (Arg-Lys-Asp), RGH-0206 (Arg-Lys-Asp-Val) and TP-5 (Arg-Lys-Asp-Val-Try) was measured using the B10LP to C57BL skin graft system and the determination of splenic T cell ratio. While thymectomy increased the period between skin grafting and rejection, each of the oligopeptides increased the number of splenic T cells and in some extent restored the rejection capacity of thymectomised C57Bl mice, presumably by restoration of thymic hormone function.\",\"PeriodicalId\":16049,\"journal\":{\"name\":\"Journal of immunopharmacology\",\"volume\":\"125 1\",\"pages\":\"67-78\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of immunopharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/08923978509026470\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of immunopharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/08923978509026470","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 3

摘要

采用B10LP - C57BL皮肤移植系统和脾T细胞比例测定，检测RGH-0205 (Arg-Lys-Asp)、RGH-0206 (Arg-Lys-Asp- val)和TP-5 (Arg-Lys-Asp- val - try)寡肽的免疫刺激作用。虽然胸腺切除术延长了植皮和排斥之间的时间，但每一种寡肽都增加了脾脏T细胞的数量，并在一定程度上恢复了胸腺切除的C57Bl小鼠的排斥能力，可能是通过恢复胸腺激素功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The effect of TP-5 and its analogs on skin grafts in mice.

The immunostimulatory action of oligopeptides RGH-0205 (Arg-Lys-Asp), RGH-0206 (Arg-Lys-Asp-Val) and TP-5 (Arg-Lys-Asp-Val-Try) was measured using the B10LP to C57BL skin graft system and the determination of splenic T cell ratio. While thymectomy increased the period between skin grafting and rejection, each of the oligopeptides increased the number of splenic T cells and in some extent restored the rejection capacity of thymectomised C57Bl mice, presumably by restoration of thymic hormone function.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of immunopharmacology

自引率

0.00%

发文量