地氟醚与七氟醚在功能性内镜鼻窦手术中恢复参数的比较研究

Harish Uppala, Mamidi Ajay Kumar, Mohd Moazzam Mohiuddin Ansari
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引用次数: 0

摘要

许多吸入麻醉剂通常用于提供成功的内窥镜鼻窦手术(ESS)所需的最佳手术场。现代吸入麻醉剂,如七氟醚和地氟醚,由于其血气分割系数低,可以快速诱导和恢复。目的:本研究的目的是比较地氟醚和七氟醚在功能性内窥镜鼻窦手术后的恢复质量。材料和方法:本研究是一项前瞻性、随机、比较临床试验,包括计划进行功能性内窥镜鼻窦手术的参与者。本研究纳入60例ASA I和II级患者,在全身麻醉下进行FESS,分为两组,每组30人:D组(地氟醚)和S组(七氟醚)。结果:两组患者年龄、性别、ASA分级、平均体重分布差异无统计学意义(p < 0.05)。两组患者的平均手术时间和麻醉时间差异无统计学意义。血流动力学变量变化不大。D组(地氟醚)睁眼时间(min)明显短于S组(七氟醚)(p<0.001)。拔管时间D组(地氟醚)(6.53±1.14)明显短于S组(七氟醚)(9.37±1.30)(p<0.001)。D组(地氟醚)服从命令时间(7.87±1.11)明显短于S组(七氟醚)(11.33±1.51)(p<0.001)。结论:在FESS患者中,地氟醚(D组)比七氟醚(S组)明显缩短了睁眼、拔管和终止麻醉的时间,因此地氟醚比七氟醚有更快的早期恢复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative study of recovery parameters of Desflurane and Sevoflurane in functional endoscopic sinus surgery
Numerous inhalant anaesthetics are often utilised to provide the optimal operating field required for successful endoscopic sinus surgery (ESS). Modern inhaled anaesthetics such as Sevoflurane and Desflurane enable rapid induction and recovery because to their low blood-gas partition coefficients. The aim: The goal of this study is to compare desflurane with sevoflurane's recovery qualities after functional endoscopic sinus surgery. Materials and methods: The present study was a prospective, randomised, comparative clinical trial that included participants scheduled to have functional endoscopic sinus surgery. The study included 60 ASA I and II patients scheduled for FESS under general anaesthesia and divided them into two groups of 30 each: group D (Desflurane) and group S (Sevoflurane). Results: There was no statistically significant difference in the age, gender, ASA grade, or mean weight distributions between the two groups (p>0.05). There was no statistically significant difference in the mean length of operation or anaesthesia between the two groups. Hemodynamic variables did not alter much. Time in minutes for eye opening (p<0.001) was significantly shorter in group D (Desflurane) than in group S (Sevoflurane). Time in minutes for extubation (p<0.001) was significantly shorter in group D (Desflurane) 6.53±1.14 than in group S (Sevoflurane) 9.37±1.30. Time in minutes for obeying commands (p<0.001) was significantly shorter in group D (Desflurane) 7.87±1.11 than in group S (Sevoflurane) 11.33±1.51. Conclusion: In patients receiving FESS time taken for eye opening, extubation and time taken for obeying commands from termination of anesthetic is significantly shorter with desflurane (group D) when compared with sevoflurane (group S). So desflurane was linked to a quicker early recovery than sevoflurane.
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