[高尿酸血症、痛风和心血管疾病]。

Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale Pub Date : 2016-03-23 DOI:10.1024/0040-5930/a000770

Ka Murray, T. Burkard

{"title":"[高尿酸血症、痛风和心血管疾病]。","authors":"Ka Murray, T. Burkard","doi":"10.1024/0040-5930/a000770","DOIUrl":null,"url":null,"abstract":"Hyperuricemia, gout as well as arterial hypertension and metabolic syndrom are highly prevalent and clinicians are frequently confronted with both conditions in the same patient. Hyperuricemia and gout are associated with cardiovascular comorbidities and a high cardiovascular risk. Despite coherent pathophysiological concepts, it remains to be determined, if this association is independent and causal. In daily clinical practice, cardiovascular risk factors should be thoroughly identified and consequently treated in all patients with hyperuricemia and gout. If preventive treatment of asymptomatic hyperuricemia with urate-lowering agents may improve cardiovascular risk and outcomes remains to be determined and is recommended only in special situations like young patients with severe hyperuricemia.","PeriodicalId":87030,"journal":{"name":"Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale","volume":"14 1","pages":"141-6"},"PeriodicalIF":0.0000,"publicationDate":"2016-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"[Hyperuricemia, gout and cardiovascular diseases].\",\"authors\":\"Ka Murray, T. Burkard\",\"doi\":\"10.1024/0040-5930/a000770\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hyperuricemia, gout as well as arterial hypertension and metabolic syndrom are highly prevalent and clinicians are frequently confronted with both conditions in the same patient. Hyperuricemia and gout are associated with cardiovascular comorbidities and a high cardiovascular risk. Despite coherent pathophysiological concepts, it remains to be determined, if this association is independent and causal. In daily clinical practice, cardiovascular risk factors should be thoroughly identified and consequently treated in all patients with hyperuricemia and gout. If preventive treatment of asymptomatic hyperuricemia with urate-lowering agents may improve cardiovascular risk and outcomes remains to be determined and is recommended only in special situations like young patients with severe hyperuricemia.\",\"PeriodicalId\":87030,\"journal\":{\"name\":\"Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale\",\"volume\":\"14 1\",\"pages\":\"141-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-03-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1024/0040-5930/a000770\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1024/0040-5930/a000770","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 5

摘要

高尿酸血症、痛风以及动脉高血压和代谢综合征非常普遍，临床医生经常在同一患者中遇到这两种情况。高尿酸血症和痛风与心血管合并症和高心血管风险相关。尽管有一致的病理生理学概念，但这种关联是否独立和因果关系仍有待确定。在日常临床实践中，所有高尿酸血症和痛风患者应彻底确定心血管危险因素并进行治疗。是否使用降尿酸药物对无症状高尿酸血症进行预防性治疗可以改善心血管风险和结果仍有待确定，仅推荐用于特殊情况，如严重高尿酸血症的年轻患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

[Hyperuricemia, gout and cardiovascular diseases].

Hyperuricemia, gout as well as arterial hypertension and metabolic syndrom are highly prevalent and clinicians are frequently confronted with both conditions in the same patient. Hyperuricemia and gout are associated with cardiovascular comorbidities and a high cardiovascular risk. Despite coherent pathophysiological concepts, it remains to be determined, if this association is independent and causal. In daily clinical practice, cardiovascular risk factors should be thoroughly identified and consequently treated in all patients with hyperuricemia and gout. If preventive treatment of asymptomatic hyperuricemia with urate-lowering agents may improve cardiovascular risk and outcomes remains to be determined and is recommended only in special situations like young patients with severe hyperuricemia.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale

自引率

0.00%

发文量