{"title":"一种用于检测血清中HIV和HCV标记物的便携式、纸质多路免疫传感器","authors":"Chen Zhao, Xinyu Liu","doi":"10.1109/TRANSDUCERS.2015.7181100","DOIUrl":null,"url":null,"abstract":"This paper reports an integrated diagnostic platform, including a paper-based electrochemical immunosensor array and a customized handheld potentiostat, for detecting protein markers of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in serum. To our best knowledge, this is the first paper-based electrochemical immunosensing platform, with multiplexing and telemedicine capabilities, for diagnosing HIV/HCV co-infection. The platform can perform simultaneous enzyme-linked immunesorbent assays (ELISAs) on 8 serum samples, produce multiple measurement data for HIV and HCV markers from a single run, and transmit the results to remote sites for telemedicine. The unique integration of paper-based microfluidics and mobile instrumentation renders our tests portable, low-cost, user-friendly, and high-throughput.","PeriodicalId":6465,"journal":{"name":"2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A portable, paper-based multiplexing immunosensor for detection of HIV and HCV markers in serum\",\"authors\":\"Chen Zhao, Xinyu Liu\",\"doi\":\"10.1109/TRANSDUCERS.2015.7181100\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This paper reports an integrated diagnostic platform, including a paper-based electrochemical immunosensor array and a customized handheld potentiostat, for detecting protein markers of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in serum. To our best knowledge, this is the first paper-based electrochemical immunosensing platform, with multiplexing and telemedicine capabilities, for diagnosing HIV/HCV co-infection. The platform can perform simultaneous enzyme-linked immunesorbent assays (ELISAs) on 8 serum samples, produce multiple measurement data for HIV and HCV markers from a single run, and transmit the results to remote sites for telemedicine. The unique integration of paper-based microfluidics and mobile instrumentation renders our tests portable, low-cost, user-friendly, and high-throughput.\",\"PeriodicalId\":6465,\"journal\":{\"name\":\"2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/TRANSDUCERS.2015.7181100\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/TRANSDUCERS.2015.7181100","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A portable, paper-based multiplexing immunosensor for detection of HIV and HCV markers in serum
This paper reports an integrated diagnostic platform, including a paper-based electrochemical immunosensor array and a customized handheld potentiostat, for detecting protein markers of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in serum. To our best knowledge, this is the first paper-based electrochemical immunosensing platform, with multiplexing and telemedicine capabilities, for diagnosing HIV/HCV co-infection. The platform can perform simultaneous enzyme-linked immunesorbent assays (ELISAs) on 8 serum samples, produce multiple measurement data for HIV and HCV markers from a single run, and transmit the results to remote sites for telemedicine. The unique integration of paper-based microfluidics and mobile instrumentation renders our tests portable, low-cost, user-friendly, and high-throughput.
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