微解剖双探针睾丸小管试验

TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference Pub Date : 2007-06-10 DOI:10.1109/SENSOR.2007.4300544

A. Ramkumar, X. Chen, D. Paduch, P.N. Schlegel, A. Lai

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引用次数: 0

摘要

我们报道了一种集成了超声致动器和多晶硅应变片的微加工硅探针，用于显微解剖睾丸精子提取(TESE)手术。在大鼠睾丸组织上进行了插入实验，通过检测菌株，我们能够确定样品中携带精子的微管的大小。该信息在显微解剖TESE中很重要，可以区分有和没有可育精子的小管，消除了目前光学精子定位所需的大切口。组织刚度测量的实验数据表明，微力学分析也可用于微创睾丸癌检测。

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Micro-Dissecting Dual-Probe Testicular Tubule Assay

We report on a microfabricated silicon probe integrated with an ultrasonic actuator and polysilicon strain gauges for Microdissection TEsticular Sperm Extraction (TESE) surgery. Insertion experiment was performed on rat testis tissue and by sensing the strain we were able to ascertain the size of the sperm-carrying microtubules in the sample. This information is important in Microdissection TESE to distinguish tubules with and without fertile sperm, eliminating large incision currently required for optical spermatazoa localization. Experimental data on tissue rigidity measurements indicate that the micromechanical assay can also be used for minimally-invasive testicular cancer detection.

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TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference

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