{"title":"尼罗替尼治疗慢性骨髓性白血病并发广泛性角化病毛毛样疹1例","authors":"Ecem Bostan, Adam Jarbou, S. Ersoy Evans","doi":"10.32552/2022.actamedica.750","DOIUrl":null,"url":null,"abstract":"Keratosis pilaris is a skin disorder which is characterized by follicular hyperkeratosis. It is most commonly seen in patients with atopic dermatitis and ichthyosis vulgaris. Abnormal keratinization of the hair follicle leads to plugging and bumpy, rough appearance. Upper extensor arms, thighs, buttocks and cheeks are most commonly affected by the disease. Even though keratosis pilaris is associated with autosomal dominant inheritance; it may also be seen as a side effect of various targeted cancer therapies including BRAF and tyrosine kinase inhibitors. Herein, we would like to present a case of keratosis pilaris that had developed secondary to nilotinib treatment.","PeriodicalId":50891,"journal":{"name":"Acta Medica Mediterranea","volume":"C-17 1","pages":""},"PeriodicalIF":0.3000,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Case of Widespread Keratosis Pilaris-like eruption Associated with Nilotinib Used for Chronic Myelogenous Leukemia\",\"authors\":\"Ecem Bostan, Adam Jarbou, S. Ersoy Evans\",\"doi\":\"10.32552/2022.actamedica.750\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Keratosis pilaris is a skin disorder which is characterized by follicular hyperkeratosis. It is most commonly seen in patients with atopic dermatitis and ichthyosis vulgaris. Abnormal keratinization of the hair follicle leads to plugging and bumpy, rough appearance. Upper extensor arms, thighs, buttocks and cheeks are most commonly affected by the disease. Even though keratosis pilaris is associated with autosomal dominant inheritance; it may also be seen as a side effect of various targeted cancer therapies including BRAF and tyrosine kinase inhibitors. Herein, we would like to present a case of keratosis pilaris that had developed secondary to nilotinib treatment.\",\"PeriodicalId\":50891,\"journal\":{\"name\":\"Acta Medica Mediterranea\",\"volume\":\"C-17 1\",\"pages\":\"\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2022-10-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Medica Mediterranea\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.32552/2022.actamedica.750\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Medica Mediterranea","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.32552/2022.actamedica.750","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A Case of Widespread Keratosis Pilaris-like eruption Associated with Nilotinib Used for Chronic Myelogenous Leukemia
Keratosis pilaris is a skin disorder which is characterized by follicular hyperkeratosis. It is most commonly seen in patients with atopic dermatitis and ichthyosis vulgaris. Abnormal keratinization of the hair follicle leads to plugging and bumpy, rough appearance. Upper extensor arms, thighs, buttocks and cheeks are most commonly affected by the disease. Even though keratosis pilaris is associated with autosomal dominant inheritance; it may also be seen as a side effect of various targeted cancer therapies including BRAF and tyrosine kinase inhibitors. Herein, we would like to present a case of keratosis pilaris that had developed secondary to nilotinib treatment.
期刊介绍:
Acta Medica Mediterranea is an indipendent, international, English-language, peer-reviewed journal, online and open-access, designed for internists and phisicians.
The journal publishes a variety of manuscript types, including review articles, original research, case reports and letters to the editor.