斯洛文尼亚的孕产妇死亡率:病例报告和确定与妊娠有关的死亡的方法

E. Kralj , B. Mihevc-Ponikvar , T. Premru-Sršen , J. Balažic
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引用次数: 5

摘要

我们报告了一名22岁初产妇发生严重子痫前期/子痫伴溶血、肝酶升高和低血小板(HELLP)综合征的致死性脑出血病例。报告病例的特点是在分娩时突然出现子痫前期/子痫,病程暴发性,肾脏的微小变化和先前存在的加速动脉硬化的迹象。由于很少有法医病理学家对此类病例有足够的经验,而且鉴别诊断可能很困难,我们认为有必要由两名法医病理学家组成的小组对所有产妇死亡进行尸检,并与产科专家合作对病例进行进一步分析。产妇死亡在发达国家很少见,但极为重要,因为它们代表了严重的产妇和新生儿发病率的"冰山一角",因为它们反映了产前和产科护理的可及性和质量以及育龄妇女的健康状况。不幸的是,它们经常在死亡证明中被错误分类,这可能导致对解决潜在问题的参与不足。在斯洛文尼亚,采用积极查找与怀孕有关的死亡人数的方法,以便能够准确监测产妇死亡率并尽量减少少报。该方法基于手工修改死亡证明和基于计算机的死亡率数据库与出生登记册和胎儿死亡登记册的联系,已被证明是高效率的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Maternal mortality in Slovenia: Case report and the method of identifying pregnancy-associated deaths

We report on the case of fatal intracerebral haemorrhage that followed the development of severe preeclampsia/eclampsia with haemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome in a 22-year-old primipara. Peculiarities of the reported case are abrupt onset of preeclampsia/eclampsia during the delivery, fulminant course of the disease, minimal changes in kidneys and signs of pre-existing accelerated arteriosclerosis. Since very few forensic pathologists have sufficient experience with such cases and the differential diagnosis may be difficult, we consider it necessary that in all maternal deaths the post-mortem examination is performed by a team of two forensic pathologists and the case further analysed in collaboration with expert obstetrician.

Maternal deaths are rare in developed countries but extremely important, because they represent the “tip of the iceberg” of severe maternal and neonatal morbidity and because they reflect accessibility and quality of prenatal and obstetric care as well as the health status of reproductive-aged women. Unfortunately, they are often misclassified in death certificates which may lead to insufficient engagement in solving underlying problems. In Slovenia, the method of active search for pregnancy-associated deaths is used in order to enable accurate monitoring of maternal mortality and minimise underreporting. The method is based on the manual revision of death certificates and the computer-based linkage of Mortality Database with birth register and foetal deaths register and has proved to be highly efficient.

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