A CASE STUDY OF NEONATAL ORGANOPHOSPHATE POISONING PRESENTED AS ACUTE RESPIRATORY DISTRESS

Introduction: Organophosphorus Compounds Intoxication [OPCI] is a likely fatal but completely manageable condition that is still quite common in our country. Early diagnosis is crucial in preventing fatality. Although rarely reported, it occurs in infants. However, history may not be forthcoming and initial presentation often deceptive. Case report: We report a case of neonate admitted to the neonatal intensive care unit (NICU) of Abu El-Reish Hospital; Faculty of Medicine; Cairo University with respiratory distress, pinpoint pupils and hypotonia. The symptoms appeared after spraying the home by insecticides. Plasma pseudocholinesterase level appeared to be low, consistent with acute intoxication with organophosphorus insecticide. Treatment: Management of OPCI consists of airway management, administration of oxygen and fluid, as well as atropine in increasing doses and obidoxime (Acetylcholine esterase reactivator). Plasma pseudocholinesterase analysis is a cheap and an easy measurement for OPCI. And it could be used for diagnosis and treatment monitoring.