唐氏综合症-痴呆发病年龄

Arvio Maria, Bjelogrlic-Laakso Nina
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引用次数: 2

摘要

背景:阿尔茨海默病是唐氏综合症患者最常见的死亡原因。这项前瞻性的、基于人群的、为期15年的随访研究旨在确定痴呆的发病年龄。方法:在基线时,98名成人首次使用当前精神状态-学习障碍评估进行筛查。这些筛查在研究期间又重复了两次。结果:老年痴呆的指示性体征在35岁后迅速增加,最常见的表现为自理能力下降、精力丧失、理解能力受损和健忘。结论:从30岁起对唐氏综合症患者进行定期随访,可以采取适当的干预措施,延缓痴呆症的进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Down Syndrome - Onset Age of Dementia
Background: Alzheimer’s disease is the most common cause of death in people who have Down syndrome. This prospective, population-based, 15-year follow-up study aimed to define the onset age of dementia. Methods: At baseline 98 adults were screened for the first time by using the Present Psychiatric State-Learning Disabilities assessment. These screenings were repeated twice more during the study. Results: The indicative signs for dementia increased rapidly after the age of 35 and appeared most frequently as reduced self-care skills, loss of energy, impaired understanding and forgetfulness. Conclusion: Regular follow-up of people who have Down syndrome from the age of 30 onward enables appropriate interventions to delay the progression of dementia.
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