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Jurnal Farmasi Udayana Pub Date : 2018-12-31 DOI:10.24843/jfu.2018.v07.i02.p01

I. G. A. N. P. Unique

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引用次数: 0

摘要

本研究旨在从姜黄根茎提取物中提取一种药膏，以获得稳定的药膏，作为一种药用药膏，其浓度有不同的酒精浓度作为一种软化剂。在这项研究中，奶油是由fl(4%)、F II(7%)和F III(10%)浓度变化制成的。所做的物理评价包括有机评价、均质性、粘性、舒适性、pH、奶油类型和粘性。测试结果显示，这三个配方产生的奶油是棕黄色的，有姜黄色的气味，也有半固体色的混合物，有良好的同质性，传播能力好，pH值是5.86;5.66;4.68和M/A乳液类型。粘度测试结果显示，粘度和粘度符合要求。粘滞动力测试表明,第三个公式奶油粘滞电源没资格sediaan局部的善工。抽象这个study aims to formulation creams来自turmeric extract (Curcuma domestica瓦尔。)得到美国马厩preparations百万《variations伤治疗奶油cetyl酒精的双臀美国stiffening探员。和variations In this study,奶油是formulated cetyl酒精的双臀F 1(4%)、F II(7%)和F三世(10%)。《formulation是evaluated basen在好几个参数,这是organoleptic调查员,homogeneity adhesion dispersion, pH值、奶油型和viscosity。《三个formulas调查员那里那个由奶油和a brownish-yellow颜色,独特turmeric味,和preparations with a semisolid奶油纹理,让祝homogeneity,祝dispersing不在乎,准备之pH namely 5 . 86;5 . 66;M - A型4.68和emulsions(水)的石油。事实证明，软纤维测试表明，软纤维具有可接受的要求。黏电源测试那里的所有奶油formulations确实不是suitable with The requirements of祝主题preparations等。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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OPTIMASI KONSENTRASI SETIL ALKOHOL SEBAGAI AGEN PENGENTAL PADA FORMULA KRIM EKSTRAK RIMPANG KUNYIT (Curcuma domestica)

ABSTRAK Penelitian ini betujuan untuk memformulasikan krim dari ekstrak rimpang kunyit (Curcuma domestica Val.) untuk memperoleh sediaan yang stabil sebagai krim obat luka dengan variasi konsentrasi setil alkohol sebagai agen pengental. Dalam penelitian ini krim diformulasikan dengan variasi konsentrasi setil alkohol F I (4%), F II (7%), dan F III (10%). Evaluasi fisik sediaan krim yang dilakukan meliputi evaluasi organoleptis, homogenitas, daya lekat, daya sebar, pH, tipe krim, dan viskositas. Hasil uji menunjukkan ketiga formula menghasilkan krim berwarna warna kuning jingga kecoklatan, bau khas kunyit, dan sediaan dengan tekstur krim semisolid, memiliki homogenitas yang baik, kemampuan menyebar yang baik, pH sediaan yaitu 5,86; 5,66; 4,68 dan tipe emulsi M/A (Minyak dalam Air). Hasil uji viskositas menunjukkan FII dan FIII memiliki viskositas yang sesuai dengan persyaratan. Uji daya lekat menunjukkan bahwa ketiga formulasi krim belum memenuhi persyaratan daya lekat sediaan topikal yang baik. ABSTRACT This study aims to formulation creams from turmeric extract (Curcuma domestica Val.) to obtain stable preparations as a wound healing cream in the variations concentration of cetyl alcohol as a stiffening agent. In this study, the cream was formulated with variations concentration of cetyl alcohol F 1 (4%), F II (7%), and F III (10%). The formulation were evaluated basen on several parameter, that are organoleptic evaluation, homogeneity, adhesion, dispersion, pH, cream type, and viscosity. The evaluation showed that the three formulas produced cream with a brownish-yellow color, a distinctive smell of turmeric, and preparations with a semisolid cream texture, had good homogeneity, good dispersing ability, pH of the preparation namely 5.86; 5.66; 4,68 and type M / A emulsions (Oil in Water). The results of the viscosity test showed that FII and FIII has viscosity that is suitable with the requirements. The sticky power test showed that all cream formulations does not suitable with the requirements of good topical preparations.

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Jurnal Farmasi Udayana

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