营养保健在预防和治疗心血管疾病方面的支持

IF 0.3 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
E. Gracheva, E. A. Starovoytova, E. Kulikov, N. Kirillova, S. Fedosenko, M. A. Balaganskaya, D. Kromka
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引用次数: 0

摘要

心血管疾病是全世界最常见的死亡原因。在这方面,有必要寻找和实施预防和治疗这类疾病的有效方法。生活方式的改变是一系列预防和治疗措施的重要组成部分,包括营养优化、增加体育活动和改掉坏习惯。目前,一个积极发展的领域是在食品中使用生物活性添加剂,以补充饮食中缺失的营养物质,保持健康。在本综述的过程中,对过去5年进行的随机临床试验进行了分析。这些研究调查了服用omega-3多不饱和脂肪酸的短期效果(对血脂谱、血压水平的影响)和长期结果(心肌梗死、中风、心血管死亡率的发展)。这种补充剂已被证明具有积极的直接效果,即降低总胆固醇,低密度脂蛋白,甘油三酯(降脂效果)。然而,对长期结果没有显著影响。它还提供了一些研究的信息,这些研究检查了补充剂的心脏保护作用,如白藜芦醇、红曲米、l -精氨酸和姜黄素。对出版物的分析表明,由于可能的降血脂、内皮保护和降压作用,这些补充剂具有降低心血管疾病发生和进展风险的潜力。营养支持可作为基础治疗的有效补充,有助于降低心血管疾病的发病率和死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nutraceutical support in the prevention and treatment of cardiovascular diseases
Cardiovascular disease is the most common cause of death worldwide. In this regard, there is a need to find and implement effective methods for the prevention and treatment of such diseases. Lifestyle modification is an important component of a complex of preventive and therapeutic measures, including nutrition optimization, increased physical activity, and breaking bad habits. Currently, an actively developing area is the use of biologically active additives to food, in order to replenish the missing nutrients in the diet and maintain health. In the course of the present review, an analysis was made of randomized clinical trials performed over the past 5 years. The studies investigated both the short-term effects of taking omega-3 polyunsaturated fatty acids (effect on the blood lipid spectrum, blood pressure levels) and longterm results (development of myocardial infarction, stroke, cardiovascular mortality). This supplement has demonstrated a positive effect on immediate outcomes, namely the reduction of total cholesterol, low-density lipoprotein, triglycerides (lipid-lowering effect). However, there was no significant effect on long-term results. It also provides information on studies that have examined the cardioprotective effects of supplements such as resveratrol, red yeast rice, L-arginine, and curcumin. An analysis of publications has shown that these supplements have the potential to reduce the risk of development and progression of cardiovascular diseases due to possible hypolipidemic, endothelial protective, and antihypertensive effects. Nutraceutical support can be an effective addition to the basic treatment and help reduce morbidity and mortality due to cardiovascular disease.
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来源期刊
Rational Pharmacotherapy in Cardiology
Rational Pharmacotherapy in Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
1.00
自引率
50.00%
发文量
79
审稿时长
6 weeks
期刊介绍: The primary goals of the Journal are consolidation of information on scientific and practical achievements in pharmacotherapy and prevention of cardiovascular diseases and continuing education of cardiologists and internists. The scientific concept of the edition suggests the publication of information on current achievements in cardiology, the results of national and international clinical trials. The Journal publishes original articles on the results of clinical trials designed to study the effectiveness and safety of drugs, analysis of clinical practice and its compliance with national and international recommendations, expert s’ opinions on a wide range of cardiology issues, associated conditions and clinical pharmacology. There is a heading “Preventive cardiology and public health” in the Journal to stimulate research interest in this highly demanded area. Memories of the outstanding people in medicine including cardiology, which are of great interest to historians of medicine, are published in "Our Mentors” heading.
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