二氧化铈纳米颗粒的体外细胞毒性及其对正常和可移植细胞系亚硝酸盐离子产生的影响

2017 IEEE 7th International Conference Nanomaterials: Application & Properties (NAP) Pub Date : 2017-09-01 DOI:10.1109/NAP.2017.8190337

O. Shydlovska, N. Zholobak

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引用次数: 0

摘要

在本研究中，我们使用离体正常细胞和转染细胞系来确定非稳定和柠檬酸稳定的二氧化铈纳米颗粒的毒性，并研究它们对亚硝酸盐离子产生的影响。实验结果表明，不同类型的二氧化铈纳米颗粒对肿瘤细胞的杀伤效果不同，对正常细胞和肿瘤细胞的杀伤效果也不同。

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In vitro cytotoxicity of cerium dioxide nanoparticles and its effect on nitrite-ion production in normal and transplantable cell lines

In the research, we were used normal cells that were received ex vivo, and transfected cell lines to establish the toxicity of non-stabilized and citrate-stabilized nanoparticles of cerium dioxide and to study their influence on the nitrite ion production. As a result, there was established the most effective concentrations of different type cerium dioxide nanoparticles and was showed the different response of normal and tumor cell lines.

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2017 IEEE 7th International Conference Nanomaterials: Application & Properties (NAP)

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